Department of Medicine
Faculty Profiles by Division

Division of Pulmonary, Allergy and Critical Care Medicine

Faculty Profiles

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photo Marc C. Gauthier, MD

Pulmonary, Allergy and Critical Care Medicine

Assistant Professor of Medicine


Phone: 412-692-2118

Office: UPMC Montefiore Hospital
3459 Fifth Avenue, NW628
Pittsburgh, PA 15213
Phone: 412-692-2118
Fax: 412-692-2260
Administrative Assistant:
Patty Geraci
Address: UPMC Montefiore Hospital
3459 Fifth Avenue, NW628
Pittsburgh, PA 15213
Phone: 412-692-2118
Fax: 412-692-2260
Education and Training
BA, Vanderbilt University, 2005
MD, Vanderbilt University, 2009
Internal Medicine Residency, University of Pittsburgh, 2012
Fellowship - Pulmonary, Allergy & Critical Care Medicine, University of Pittsburgh, 2016
Research Interest
My research focuses on identifying steroid resistant pathways of inflammation in severe asthma. We have previously identified Type 1 inflammation, manifested by Interferon-gamma elevation in the lung, as a phenotype of severe asthma. My current work seeks to better understand the immune mechanisms leading to persistence of Type 1 inflammation in severe asthma and how this impacts disease severity and response to currently available asthma therapies.
Clinical Interest
My clinical interest is in the diagnosis and management of patients with severe asthma. This includes management of common asthma comorbidities and newly developed biologic therapies for severe asthma.
Educational Interest
My educational interests focus on teaching medical students about asthma physiology, diagnosis and management. I also have an educational focus on critical care training for residents through the teaching services in the ICU setting.
For my complete bibliography, Click Here.
Selected Publications:
Gauthier M, Chakraborty K, Oriss TB, Raundhal M, Das S, Chen J, Huff R, Sinha A, Fajt M, Ray P, Wenzel SE, Ray A. Severe Asthma in Humans and Mouse Model Suggests a CXCL10 Signature Underlies Corticosteroid-resistant Th1 Bias. JCI Insight. 2017; Jul 6; 2(13): e94580.
Gauthier M, Ray A, Wenzel SE. Evolving Concepts of Asthma. Am J Respir Crit Care Med. 2015; 192(6): 660-8.
Sponsored Research/Activities
Title: he CXCL10-CXCR3 Axis in the Pathogenesis of Steroid-Refractory Severe Asthma
Role: Principal Investigator
Funding Agency: Parker B. Francis Foundation
Grant Number: FELLOW
Start Year: 2018
End Year: 2021
Title: Translational Training Program in Pulmonary Biology and Medicine
Role: Post Doctoral Scholar
Funding Agency: National Heart, Lung, & Blood Institute
Grant Number: T32 HL007563
Start Year: 2013
End Year: 2018
Notable Achievements
Parker B. Francis Award, 2018
American Thoracic Society, Abstract Award, 2018
14th Annual Respiratory Disease Young Investigators’ Forum, 2018
12th Annual Respiratory Disease Young Investigators’ Forum, 2016
History of Medicine Lecture Prize, Vanderbilt University School of Medicine, 2008