Department of Medicine
Faculty Profiles by Division

Division of Pulmonary, Allergy and Critical Care Medicine

Faculty Profiles

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photo Ricardo H. Pineda, PhD

Pulmonary, Allergy and Critical Care Medicine

Research Assistant Professor

Email: pinedar@upmc.edu

Phone: 412-648-7784

Contact
Office: UPMC Montefiore Hospital, NW628
3459 Fifth Avenue
Pittsburgh, PA 15213
 
Phone: 412-648-7784
Fax:
E-mail: pinedar@upmc.edu
Administrative Assistant:
Cindy Vinkovich
Email: vinkovichc@upmc.edu
Phone: 412-648-7784
Education and Training
Education
BS, National Autonomous University of Mexico School of Sciences
MS (Physiology & Biophysics), National Autonomous University of Mexico (UNAM) Biomedical Research Institute
PhD (Physiology and Neuroscience), National Autonomous University of Mexico (UNAM) Biomedical Research Institute
Research Interest
My research focuses on studying the cellular and molecular mechanisms involved in the pathology of age-related lung diseases. Currently, my research uses a translational approach using human precision-cut lung slices to model chronic lung diseases, such as Idiopathic pulmonary fibrosis and chronic obstructive pulmonary disease, to identify novel biomarkers, therapeutic targets, and treatments.
Publications
Selected Publications:
Acharya AP, Tang Y, Bertero T, Tai YY, Harvey LD, Woodcock CC, Sun W, Pineda RH, Mitash N, Königshoff M, Little SR, Chan SY. Simultaneous pharmacologic inhibition of YES-Associated protein 1 and glutaminase 1 via inhaled poly(lactic-co-glycolitic) acid-encapsulated microparticles improves pulmonary hypertension. J Am Heart Assoc. 2021; 10(12): e019091.
Alsafadi NH, Uhl FE, Pineda RH, Bailey KE, Rojas M, Wagner DE. Applications and approaches for three-dimensional precision-cut lung slices. Disease modeling and drug discovery. Am J Respir Cell Mol Biol. 2020; 62(6): 681-691.
Pineda RH, Hypolite J, Lee S, Carrasco A, Iguchi N, Meacham RB, Malykhina AP. Altered detrusor contractility and voiding patterns in mice lacking the mechanosensitive TREK-1 channel. BMC Urol. 2019; 19(1): 40.
Nedumaran B, Pineda RH, Rudra P, Lee S, Malykhina AP. Association of genetic polymorphisms in the pore domains of mechano-gated TREK-1 channels with overactive lower urinary tract symptoms in humans. Neurourol. Urodyn. 2018; 38(1): 144-150.
Pineda RH, Nedumaran B, Hypolite J, Pan XQ, Wilson S, Meacham RB, Malykhina AP. Altered expression and modulation of the two-pore domain (K2p) mechano-gated potassium channel TREK-1 in overactive human detrusor. American Journal of Physiology/Urology. 2017; 313(2): F535-F546.
Notable Achievements
Postdoctoral Fellowship, National Council of Science and Technology Mexico, 1999-2001
PhD Distinguished Student Fellowship, National Autonomous University of Mexico Foundation, 1997-1999
National Council of Science and Technology Mexico, 1993-1995
Parkinson Disease Research Foundation Fellowship, 1990-1994