Department of Medicine
Faculty Profiles by Division

Division of Pulmonary, Allergy and Critical Care Medicine

Faculty Profiles

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photo Tomeka L. Suber, MD, PhD

Pulmonary, Allergy and Critical Care Medicine

Assistant Professor of Medicine

Email: subertl2@upmc.edu

Phone: 412-692-2211

Contact
Office: UPMC Montefiore Hospital
3459 Fifth Avenue, NW628
Pittsburgh, PA 15213
 
Phone: 412-692-2211
Fax: 412-692-2260
E-mail: subertl2@upmc.edu
Administrative Assistant:
Shannon McKenzie
Address: UPMC Montefiore Hospital
3459 Fifth Avenue, NW628
Pittsburgh, PA 15213
Email: mckenziesj@upmc.edu
Phone: 412-692-2211
Fax: 692-692-2260
Education and Training
Education
BS,Chemistry, University of North Carolina at Chapel Hill, 2002
MD, Johns Hopkins University School of Medicine, 2010
Ph.D., Cellular and Molecular Medicine, Johns Hopkins University School of Medicine, 2010
Training
Internship in Internal Medicine, Johns Hopkins Hospital, 2011
Resident in Internal Medicine, Johns Hopkins Hospital, 2013
Fellow in Pulmonary and Critical Care Medicine, University of Pittsburgh School of Medicine, 2018
Research Interest
Dr. Suber studies host defense mechanisms in intrapulmonary bacterial infections that lead to acute respiratory distress syndrome. She has also studied how regulation of protein stability by the ubiquitin-proteasome pathway modulates lung epithelial responses during inflammation.
Clinical Interest
Dr. Suber's clinical interests include acute respiratory distress syndrome, sepsis, and bacterial pulmonary infections including Klebsiella pneumoniae and Streptococcal pneumoniae.
Educational Interest
Dr. Suber is actively involved in the recruitment and retention of talented internal medicine trainees to the University of Pittsburgh. She also teaches medical students and residents in the medical intensive care unit.
Publications
For my complete bibliography, Click Here.
Selected Publications:
Suber TL, Nikolli I, O'Brien ME, Londino J, Zhao J, Chen K, Mallampalli RK, Zhao Y. FBXO17 promotes cell proliferation through activation of Akt in lung adenocarcinoma cells. Respir Res. 2018; Oct 25;19(1): 206.
Suber T, Wei J, Jacko AM, Nikolli I, Zhao Y, Zhao J, Mallampalli RK. SCFFBXO17 E3 ligase modulates inflammation by regulating proteasomal degradation of glycogen synthase kinase-3ß in lung epithelia. The Journal of Biological Chemistry. 2017; 292(18): 7452-7461.
Suber T, Mallampalli RK. An Emerging Role for Megalin as a Regulator of Protein Leak in Acute Lung Injury. Am J Respir Cell Mol Biol. 2017; Nov;57(5): 504-505.
Cai J, Wei J, Li S, Suber T, Zhao J. AM966, an Antagonist of Lysophosphatidic Acid Receptor 1, Increases Lung Microvascular Endothelial Permeability through Activation of Rho Signaling Pathway and Phosphorylation of VE-Cadherin. Mediators Inflamm. 2017; 2017:6893560: Epub2017Feb27.PubMedPMID:28348461.
Sponsored Research/Activities
Title: A Role for Itaconate in Host Defense Against Klebsiella Pneumoniae Infection
Role: Principal Investigator
Funding Agency: Samuel and Emma Winters Foundation
Start Year: 2019
End Year: 2020
Title: Regulation of GSK3B Degradation and its Role in Acute Lung Injury
Role: Principal Investigator
Funding Agency: National Heart, Lung, & Blood Institute
Grant Number: F32 HL137248
Start Year: 2017
End Year: 2019
Title: The role of ACOD1 in immunomodulation in intrapulmonary Klebsiella pneumoniae infection
Role: Co-Investigator
Funding Agency: National Heart, Lung, & Blood Institute
Grant Number: R01 HL142084
Start Year: 2019
End Year: 2022
Notable Achievements
Burroughs Wellcome Fund Postdoctoral Enrichment Program, 2017
Robert M. Rogers Outstanding Scholarly Achievement Award, University of Pittsburgh, Division of Pulmonary, Allergy, and Critical Care Medicine, 2017
Ruth L. Kirschstein Postdoctoral Individual National Research Service Award, 2017