Department of Medicine
Faculty Profiles by Division

Division of Cardiology

Faculty Profiles

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photo Joon Sup Lee, MD


Associate Professor of Medicine

President, Physician Services Division

Vice Dean for Clinical Affairs, School of Medicine


Phone: 412-647-5944

Office: 3600 Forbes Ave at Meyran St
Forbes Tower, Ninth Floor, Suite 9019
Pittsburgh, PA 15213
Phone: 412-647-5944
Fax: 412-647-1919
Administrative Assistant:
Cheri Hepfl
Phone: 412-647-5944
Education and Training
BA, Dartmouth College, 1984
MD, Duke University School of Medicine, 1988
Internal Medicine, Massachusetts General Hospital, 1991
Chief Resident, Massachusetts General Hospital, 1992
Cardiology, Massachusetts General Hospital, 1995
Interventional Cardiology, Massachusetts General Hospital, 1996
Research Interest
Dr. Lee has a specific research interest in the role of gene therapy cell based therapy in cardiovascular disease and has been involved in organizing local and multicenter trials regarding the potential role of these novel therapies in the treatment of coronary disease. Dr. Lee has been active in establishing the Transcatheter Aortic Valve Replacement(TAVR) program at UPMC in conjunction with the cardiac surgical colleagues. UPMC has one of the leading TAVR programs in the country.
Clinical Interest
Dr. Joon Lee is Division Chief of Cardiology and Executive Director of the UPMC's Heart and Vascular Institute (HVI). His clinical interests are in the area of interventional cardiology, catheter based valve replacement and models of care delivery. He also serves as the central clinical liaison between the HVI at Presbyterian Hospital and the multiple cardiology divisions in UPMC's affiliated institutions, including St. Margaret's Hospital, Passavant Hospital, and Magee Women's Hospital among others. In this administrative capacity, Dr. Lee has been successful in bringing these many institutions together in forging an environment that promotes collaboration in the clinical and research arenas.
For my complete bibliography, Click Here.
Selected Publications:
Lee, J. S., Feldman, A. M. Gene Therapy for Therapeutic Myocardial Angiogenesis: A Promising Synthesis of Two Emerging Technologies. Nature Medicine. 1998; 4(6): 739-42.
Cohen, H. A., Zenati, M., Smith, A. J. C., Lee, J. S., Chough, S., Jafar, Z., Counihan, P. J., Izzo, M., Burchenal, J. E., Feldman, A. M., Griffith, B. Feasibility of Combined Percutaneous Transluminal Angioplasty and Minimally Invasive Direct Coronary Artery Bypass in Patients with Multivessel Coronary Artery Disease. Circulation. 1998; 98(11): 1048-50.
Villanueva, F. S., Abraham, J. A., Schreiner, G. F., Csikari, M., Fischer, D., Mills, J. D., Schellenberger, U., Koci, B. J., Lee, J. S. Myocardial contrast echocardiography can be used to assess the microvascular response to vascular endothelial growth factor-121. Circulation. 2002; 105(6): 759-65.
Marroquin, O. C., Selzer, F., Mulukutla, S. R., Williams, D. O., Vlachos, H., Wilensky, R. L., Tanguay, J. F., Holper, E., Abbott, J. D., Lee, J. S., Smith, C,, Anderson W. D., Kelsey S. F., Kip, K. E. A comparison of bare metal and drug-eluting stents for off-label indications. New England Journal of Medicine. 2008; 358: 342-352.
Nair, P. K., Marroquin, O. C., Mulukutla, S. R., Khandhar, S., Gulati, V., Schindler, J. T., Lee, J. S. Clinical utility of regadenoson for assessing fractional flow reserve. JACC: Cardiovascular Interventions. 2011; 4(10): 1085-92.
Chu, D., Anastacio, M. M., Mulukutla, S. R., Lee, J. S., Smith, A. J., Marroquin, O. C., Sanchez, C. E., Morell, V. O., Cook, C. C., Lico, S. C., Wei, L. M., Badhwar, V. Safety and efficacy of implementing a multidisciplinary heart team approach for revascularization in patients with complex coronary artery disease: an observational cohort pilot study. JAMA Surgery. 2014; 149(11): 1109-12.
Olafiranye, O., Vlachos, H., Mulukutla, S. R., Marroquin, O. C., Selzer, F., Kelsey, S. F., Williams, D. O., Strollo, P. J., Reis, S. E., Lee, J. S., Smith, A. J. Comparison of long-term safety and efficacy outcomes after drug-eluting and bare-metal stent use across racial groups: Insights from NHLBI Dynamic Registry. International Journal of Cardiology. 2015; 184: 79-85.
Sanchez, C. E., Dota, A., Badhwar, V., Kliner, D., Smith, A. J., Chu, D., Toma, C., Wei, L., Marroquin, O. C., Schindler, J., Lee, J. S., Mulukutla, S. R. Revascularization heart team recommendations as an adjunct to appropriate use criteria for coronary revascularization in patients with complex coronary artery disease. Catheterization and Cardiovascular Interventions. 2015.
Cavalcante, J. L., Rijal, S., Althouse, A. D., Delgado-Montero, A., Katz, W. E., Schindler, J. T., Crock, F., Harinstein, M. E., Navid, F., Gleason, T. G., Lee, J. S. Right Ventricular Function and Prognosis in Patients with Low-Flow, Low-Gradient Severe Aortic Stenosis. Journal of the American Society of Echocardiography. 2016; 29(4): 325-33.
Notable Achievements
Fellow, American College of Cardiology, 1998
Board of Directors, American Heart Association, Pittsburgh Chapter, 2007-2011
President, American Heart Association, Pittsburgh Chapter, 2009-2012
Ad Hoc Reviewer, New England Journal of Medicine, 2012-2014
Board of Directors, UPMC Passavant Hospital, 2006-Present
Board of Directors, The Beckwith Institute, 2013-Present