Department of Medicine
Faculty Profiles by Division

Division of Cardiology

Faculty Profiles

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photo Steven Reis, MD


Professor of Medicine and Emergency Medicine

Director, University of Pittsburgh Clinical & Translational Institute

Associate Vice Chancellor for Clinical Research, Health Sciences

Director, LHAS Women's Heart Center


Phone: 412-648-9516

Office: Scaife 401
3550 Terrace Street
Pittsburgh, PA 15261
Phone: 412-648-9516
Fax: 412-648-2741
Administrative Assistant:
Lisa Pilewski
Education and Training
Bachelor of Science, Massachusetts Institute of Technology, 1983
Medical Doctor, Harvard Medical School, 1987
Internship, Internal Medicine, Brigham and Women's Hospital, 1988
Residency, Internal Medicine, Brigham and Women's Hospital, 1990
Fellowship, Cardiovascular Diseases, Johns Hopkins Hospital, 1994
Research Interest
Dr. Reis’ research interests include cardiovascular health and heart disease in women, racial disparities in cardiovascular disease, microvascular angina, endothelial function, and cardiovascular risk. Dr. Reis, who has experience as a volunteer firefighter, has also conducted cardiovascular research on firefighters, a group prone to cardiac arrest given firefighting's combination of heat, exertion, and dehydration. He and other researchers have explored methods and technologies to regulate body temperature and reduce inflammation and cardiovascular strain on active firefighters.
He is the founding director of the Clinical and Translational Science Institute (CTSI), which improves efficiency and reduces the time it takes to translate biomedical advances into societal health practices. Pitt's CTSI is part of a national consortium of research institutes funded by the National Institutes of Health. CTSI fosters collaborative research that advances new medical therapies and technologies in clinical care while training clinical scientists and ensuring greater access to clinical trials for patients and the public.
Educational Interest
As PI of the University of Pittsburgh Clinical and Translational Science Award (CTSA) program, I founded the Clinical and Translational Science Institute (CTSI) to overcome seemingly insurmountable barriers to translational research. I led an organization change at the University of Pittsburgh that 1) realigned traditional administrative structures to create a new academic discipline of clinical and translational science, 2) refocused methods of training scientists to develop a cadre of team-oriented interdisciplinary clinical and translational scientists, 3) transformed the fundamental approach to research into one that nurtures and supports innovative multidisciplinary translational science, and 4) engaged the community and health professionals in every stage of the research process from the development and testing of relevant study hypotheses through the translation of research findings to practice. As the academic home for clinical and translational science in western Pennsylvania since 2006, CTSI launched 21 research education programs, trained nearly 1,000 scientists, educates >10,000 middle and high school students annually, and enables >200 faculty and >600 investigators annually from >70 disciplines to conduct >1,000 research studies each year. Clinical and translational scientists supported by CTSI have excelled in the development of new biomedical knowledge, translated that knowledge bidirectionally across the entire translational research spectrum and to clinical practice, and published several thousands of manuscripts. These accomplishments enabled CTSI to become a national leader in the discipline of clinical and translational science.
For my complete bibliography, Click Here.
Selected Publications:
Aiyer, A. N., Kip, K. E., Mulukutla, S. R., Marroquin, O. C., Hipps Jr., L., Reis, S. E. Predictors of significant short-term increases in blood pressure in a community-based population. American Journal of Medicine. 2007; 120: 960-7.
Mulukutla, S. R., Venkitachalam, L., Bambs, C., Kip, K. E., Aiyer, A., Marroquin, O. C., Reis, S. E. Black race is associated with digital artery endothelial dysfunction: Results from the Heart SCORE study. European Heart Journal. 2010; 31: 2808-15.
Bambs, C. E., Kip, K. E., Dinga, A., Mulukutla, S. R., Aiyer, A. N., Reis, S. E. Low Prevalence of “Ideal Cardiovascular Health” in a Community-Based Population: The Heart Strategies Concentrating on Risk Evaluation (Heart SCORE) Study. Circulation. 2011; 123: 850-7.
Kip, K. E., Marroquin, O. C., Kelley, D. E., Johnson, B. D., Kelsey, S. F., Shaw, L. J., Rogers, W. J., Reis, S. E. Clinical importance of obesity versus the metabolic syndrome on cardiovascular risk in women: A report from the Women’s Ischemia Syndrome Evaluation (WISE) study. Circulation. 2004; 109: 706-13.
Reis, S. E., McDonald, M. C., Byers, S. J. Crossing the research valleys of death: The University of Pittsburgh Approach. Clinical and Translational Science. 2008; 1: 9-10.
Reis, S. E., Patterson, P. D., FitzGerald, G. A., Ford, D., Sherwin, R. S., Solway, J., Evanoff, B. A. The sharing partnership for innovative research in translation (SPIRiT) consortium: A model for collaboration across CTSA sites. Clinical and Translational Science. 2013; 6: 85-87.
Johnson, B. D., Kip, K., Marroquin, O., Ridker, P. M., Kelsey, S. F., Shaw, L. J., Pepine, C. J., Sharaf, B. L., Bairey Merz, C. N., Sopko, G., Olson, M. B., Reis, S. E. Serum amyloid A as a predictor of coronary artery disease and cardiovascular outcome in women. The NHLBI-sponsored Women’s Ischemia Syndrome Evaluation (WISE) study. Circulation. 2004; 109: 726-32.
Notable Achievements
Member, American Society for Clinical Investigation