Department of Medicine
Faculty Profiles by Division

Division of Cardiology

Faculty Profiles
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photo Matthew L Steinhauser, MD

Cardiology

Associate Professor of Medicine

Email: msteinhauser@pitt.edu

Phone: 412-383-7054
Contact
Office: 100 Technology Center Drive
Suite 558
Pittsburgh, PA 15219
 
Phone: 412-383-7054
Fax: 412-383-9055
E-mail: msteinhauser@pitt.edu
Administrative Assistant:
Kathy Brickett
Address: 100 Technology Drive; 571.1
Pittsburgh, PA 15219
Email: kab389@pitt.edu
Phone: 416-416-4416
Administrative Assistant:
Tina Furlano
Address: 200 Lothrop Street
HVI PUH 711.2 WC
Pittsburgh, PA 15213
Email: furlanot@upmc.edu
Phone: 412-802-3131
Fax: 412-648-6358
Education and Training
Education
MD, University of Michigan Medical School, 2002
Training
Internship, Columbia University Medical Center, 2003
Residency, Columbia University Medical Center, 2005
Chief Resident, Columbia University Medical Center, 2006
Clinical and Research Fellowship, Brigham and Women's Hospital, 2011
Clinical Interest
Dr. Steinhauser's clinical interests include General Cardiology and Cardiovascular Prevention.
Publications
For my complete bibliography, Click Here.
Selected Publications:
Fazeli PK, Lun M, Kim SM, Bredella MA, WRight S, Zhang Y, Lee H, Catana C, Klibanski A, Patwari P, Steinhauser ML. FGF21 and the late adaptive response to starvation in humans. Journal of Clinical Investigation. 2015; 125: 4601-11.
Chu AY, Deng X, Fisher VA, Drong A, Zhang Y, Feitosa MF, Liu CT, Weeks O, Choh AC, Duan Q, Dyer TD, Eicher JD, Guo X, Heard-Costa NL, Kacprowski T, Kent JW Jr, Lange LA, ..., Steinhauser ML, Fox CS. Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation. Nature Genetics. 2017; 49: 125-30.
Guillermier C, Fazeli PK, Kim S, Lun M, Zuflacht JP, Milian J, Lee H, Francios Saint Cyr H, Horreard F, Larson D, Rosen ED, Lee RT, Lechene CP, Steinhauser ML. Imaging mass spectrometry demonstrates age related decline in human adipose plasticity. JCI Insight. 2017; 2: e90349.
Zhang y, Federation AJ, Kim S, O'Keefe J, Lun M, Xiang D, Brown JD, Steinhauser ML. Targeting nuclear receptor NR4A1 dependent adipocyte progenitor quiescence promotes metabolic adaptation to obesity. Journal of Clinical Investigation. 2018; 128(11): 4898-4911.
Narendra DP, Guillermier C, Gyngard F, Huang X, Ward ME, Steinhauser ML. Coupling APEX labeling to imaging mass spectrometry of single organelles reveals heterogeneity in lysosomal protein turnover. Journal of Cell Biology. 2020; 219(1): e201901097.
Zhang Y, Guillermier C, De Raedt T, Cos A, Maertens O, Yimlamai D, Lun M, Whitney A, Maas RL, Goessling W, Cichowski K, Steinhauser ML. Imaging mass spectrometry reveals tumor metabolic heterogeneity. iScience. 2020; 23(8): 101355.
Steinhauser ML, Olenchock BA, O'Keefe J, Lun M, Pierce KA, Lee H, Pantano L, Klibanski A, Shulman GI, Clish CB, Fazeli PK. The circulating metabolome of human starvation. JCI Insight. 2018; 3(16).
Kim SM, Lun M, Wang M, Senyo S, Guillermier C, Patwari P, Steinhauser ML. Loss of White Adipose Hyperplastic Potential is Associated with Enhanced Susceptibility to Insulin Resistance. Cell Metabolism. 2014; 20(6): 1049-1058.
Sponsored Research/Activities
Title: Quantification of the decline of heart muscle cell proliferation and its reversal in pediatric patients
Role: Principal Investigator
Funding Agency: National Heart, Lung, & Blood Institute
Grant Number: R01 HL151386
Start Year: 2020
End Year: 2024
Title: Elucidating the chromatin-dependent mechanisms governing chronic inflammatory activation of endothelial cells in Artherosclerosis
Role: Principal Investigator
Funding Agency: Vanderbilt University / National Heart, Lung, & Blood Institute
Grant Number: R01 HL146654
Start Year: 2020
End Year: 2022
Title: Quantification of the decline of heart muscle cell proliferation and its reversal in pediatric patients
Role: Principal Investigator
Funding Agency: National Institute of Health
Grant Number: R01
Start Year: 2020
End Year: 2021
Title: ELUCIDATING THE GOVERNING CHRONIC INFLAMMATORY ACTIVATION OF ENDOTHELIAL CELLS IN ARTHEROSCLEROSIS
Role: Principal Investigator
Funding Agency: Vanderbilt University / National Heart, Lung, & Blood Institute
Grant Number: R01 HL146654
Start Year: 2020
End Year: 2021
Title: A new modality to image tumor metabolic heterogeneity at subcellular resolution
Role: Principal Investigator
Funding Agency: National Cancer Institute
Grant Number: DP2
Start Year: 2020
End Year: 2021
Title: A new modality to image tumor metabolic heterogeneity at subcellular resolution
Role: Principal Investigator
Funding Agency: National Cancer Institute
Grant Number: DP2
Start Year: 2020
End Year: 2021
Title: Functional evaluation of a new GWAS locus that links visceral adiposity and type 2 diabetes
Role: Principal Investigator
Funding Agency: National Institute of Diabetes, Digestive, & Kidney Disease
Grant Number: R01 DK120659
Start Year: 2019
End Year: 2023
Notable Achievements
Board Certified, Internal Medicine, 2005
Board Certified, Cardiovascular Disease, 2009

Division Websites

Cardiology

Endocrinology and Metabolism

Gastroenterology, Hepatology and Nutrition

General Internal Medicine

Geriatric Medicine
Hematology/Oncology

Infectious Diseases

Pulmonary, Allergy and Critical Care Medicine

Renal-Electrolyte

Rheumatology and Clinical Immunology

Contact

Department of Medicine
1218 Scaife Hall
3550 Terrace Street
Pittsburgh, PA 15261
Email:  chairoff@pitt.edu
Phone:  412-648-9636
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