Department of Medicine
Faculty Profiles by Division

Division of General Internal Medicine

Faculty Profiles

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photo Cristina M. Murray-Krezan, PhD

General Internal Medicine

Associate Professor of Medicine

Associate Director for Clinical Trials, Center for Research on Healthcare Data Center

Co-Director, Center for Clinical Trials Data Coordination

Associate Director, Department of Medicine Postdoctoral Training Program


Phone: 412-864-3023

Office: 200 Meyran Ave
Suite 300
Pittsburgh, PA 15213
Phone: 412-864-3023
Education and Training
BS, Astrophysics, University of New Mexico, 2001
MS, Statistics, University of Virginia, 2006
PhD, Statistics, University of New Mexico, 2021
Research Interest
Dr. Murray-Krezan’s clinical research interests are wide and varied, with a focus in recent years on substance use disorders, as well as interventions to improve the health and well-being of marginalized, underserved, and underrepresented populations. She also has an interest in women’s health. She has been involved in clinical trials research since 2007 and has an affinity for patient-centered trials with complex behavioral and medical interventions. Additionally, Dr. Murray-Krezan is dedicated to the success, growth, and integration of data coordination in multi-site clinical trials and observational studies. This includes research in the areas of novel or best study designs, recruitment and retention methods, and integration of pragmatic approaches for study outcomes. Statistical research interests include developing new methods to identify and correct for informative drop-out in the survival analytic framework.
Educational Interest
Dr. Murray-Krezan has extensive teaching experience for graduate students in clinical research programs. In Pitt’s Institute for Clinical Research Education (ICRE), she teaches the Regression & ANOVA course and co-teaches the Clinical Research Methods course. She is also a guest instructor for the ICRE’s Advanced Grant Writing course, providing study design and other biostatistics-focused feedback on students’ draft research proposals. Dr. Murray-Krezan works with K scholars, provides research mentorship to junior investigators, and is the Associate Director for the DOM Postdoctoral Training Program. At the University of New Mexico, Dr. Murray-Krezan taught Biostatistics for Translational Research in their Master of Science in Clinical Research program for 10 years. She also served on multiple thesis committees and provided research mentorship to dozens of medical and health science trainees and junior faculty.
For my complete bibliography, Click Here.
Selected Publications:
Ober AJ, Murray-Krezan C, Page K, Friedmann PD, Chan Osilla K, Ryzewicz S, Huerta S, Mazer MW, Leamon I, Messineo G, Watkins KE, Nuckols T, Danovitch I. The Substance Use Treatment and Recovery Team (START) study: protocol for a multi-site randomized controlled trial evaluating an intervention to improve initiation of medication and linkage to post-discharge care for hospitalized patients with opioid use disorder. Addiction Science & Clinical Practice. 2022; 17(1): 39.
Rodriguez L, Murray-Krezan C, Regino L, Tellez M, Vasquez C, Sandoval V, Perez Rodriguez D, Pedigo B, Page-Reeves J. A Study of a Culturally and Contextually Situated Multimedia Approach to Recruit a Hard-to-Reach Spanish-Speaking Population for a Randomized Control Trial (RCT). Journal of Empirical Research on Human Research Ethics. 2022; Epub ahead of print.
Page, K., Murray-Krezan, C., Leeman, L., Carmody, M., Stephen, J. M., Bakhireva, L. N. Prevalence of marijuana use in pregnant women with concurrent opioid use disorder or alcohol use in pregnancy. Addict Sci Clin Pract. 2022; 17(1): 3.
Meredith, L. S., Komaromy, M. S., Cefalu, M., Murray-Krezan, C., Page, K., Osilla, K. C., Dopp, A. R., Leamon, I., Tarhuni, L., Hindmarch, G., Jacobsohn, V., Watkins, K. E., CLARO Study Group. Design of CLARO (Collaboration Leading to Addiction Treatment and Recovery from other Stresses): A randomized trial of collaborative care for opioid use disorder and co-occurring depression and/or posttraumatic stress disorder. Contemp Clin Trials. 2021; 106354.
Page-Reeves, J., Murray-Krezan, C., Regino, L., Perez, J., Bleecker, M., Perez, D., Wagner, B., Tigert, S., Bearer, E. L., Willging, C. E. A randomized control trial to test a peer support group approach for reducing social isolation and depression among female Mexican immigrants. BMC Public Health. 2021; 21(1): 119.
Crisanti, A. S., Murray-Krezan, C., Reno, J., Killough, C. Effectiveness of Peer-Delivered Trauma Treatment in a Rural Community: A Randomized Non-inferiority Trial. Community Ment Health J. 2019; 55(7): 1125-1134.
Notable Achievements
Appointed as Co-Chair of PCORI Clinical Advisory Panel, 2022
Appointed to PCORI Clinical Trials Advisory Panel, 2021