Department of Medicine
Faculty Profiles by Division

Department of Medicine

Faculty Profiles

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photo Catherine Baty, DVM, PhD

Renal-Electrolyte

Research Assistant Professor, Renal Electrolyte Division

Email: cjb16@pitt.edu

Phone: 412-648-9411

Contact
Office: 3550 Terrace Street
Pittsburgh, 15261
 
Phone: 412-648-9411
Fax:
E-mail: cjb16@pitt.edu
Education and Training
Education
DVM, College of Veterinary Medicine, University of Minnesota, 1998
PhD, North Caorlina State University, 1997
PhD Program, Small Animal Internal Medicine, North Carolina State University
Training
Internship, Small Animal Rotating, North Carolina State University, 1989
Post-doctoral fellow, University of Oxford, 1999
Post-doctoral fellow, Medical University of South Carolina, 2002
Research Interest
Dr. Baty’s research interests focus on the role of lymphatic vasculature in health and disease. She collaborated with geneticists Robert Ferrell and David Finegold to first identify connexin mutations as a cause of lymphedema in humans. She is using a high speed confocal imaging perfusion system for studies of renal lymphatics, ex vivo kidney slice cultures, perfused renal proximal tubules and renal blood flow imaging.
Clinical Interest
Dr. Baty is a Diplomate of the American College of Veterinary Internal Medicine, boarded in small animal internal medicine. Her veterinary clinical interests are mostly cardiovascular, especially the natural history and genetics of feline hypertrophic cardiomyopathy.
Publications
For my complete bibliography, Click Here.
Selected Publications:
Navina, S., Acharya, C., DeLany, J.P., Orlichenko, L.S., Baty, C.J., Shiva, S.S., Durgampudi, C., Karlsson, J.M., Lee, K., Bae, K.T., Furlan, A., Behari, J., Liu, S., McHale, T., Nichols, L., Papachistou, G.I., Yadavm D., Singh, V.P. Lipotoxicity causes multisystem organ failure and exacerbates acute pancreatitis in obesity. Science Translational Medicine. 2011; 3(107): 107ra110.
Sachdev, U., Cui, X., Hong, G., Namkoong, S., Karlsson, J.M., Baty, C.J., Tzeng, E. High mobility group box 1 promotes endothelial cell angiogenic behavior in vitro and improves muscle perfusion in vivo in response to ischemic injury. Journal of Vascular Surgery. 2012; 55(1): 180-91.
Montecalvo, A., Larregina, A.T., Shufesky, W.J., Stolz, D.B., Sullivan, M.L., Karlsson, J.M., Baty, C.J., Gibson, G.A., Erdos, G., Wang, Z., Milosevic, J., Tkacheva, O.A., Divito, S.J., Jordan, R., Lyons-Weiler,J., Watkins, S.C., Morelli, A.E. Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes. Blood. 2012; 119(3): 756-66.
Finegold, D.N., Baty, C.J., Knickelbein, K.Z., Perschke, S., Noon, S.E., Campbell, D., Karlsson, J.M., Huang, D., Kimak, M.A., Lawrence, E.C., Feingold, E., Meriney, S.D., Brufsky, A.M, Ferrell, R.E. Connexin 47 mutations increase risk for secondary lymphedema following breast cancer treatment. Clinical cancer research:an official journal of the American Association for Cancer Research. 2012; 18(8): 2382-90.
Mishra, V., Cline, R., Noel, P., Karisson, J., Baty, C.J., Orlichenko, L., Patel, K., Trivedi, R.N., Husain, S.Z., Acharya, C., Durgampudi, C., Stolz, D.B., Navina, S., Singh, V.P. Src Dependent Pancreatic Acinar Injury Can Be Initiated Independent of an Increase in Cytosolic Calcium. PloS one. 2013; 8(6): e66471.
Kenche, H., Baty, C.J., Vedagirl, K., Shapiro, S.D., Blumental-Perry, A. Cigarette smoking affects oxidative protein folding in endoplasmic reticulum by modifying protein disulfide isomerase. FASEB journal: official publication of the Federation of American Societies for Experimental Biology. 2013; 27(3): 965-77.
Acharya, C., Cline, R.A., Jaligama, D., Noel, P., Delany, J.P., Bae, K., Furlan, A., Baty, C.J., Karlsson, J.M., Rasario, B.L., Patel K., Mishra, V., Bugampudi, C., Yadav, D., Navina, S., Singh, V.P. Fibrosis reduces severity of acute-on-chronic pancreatitis in humans. Gastroenterology. 2013; 145(2): 466-75.
Chu,C.T., Ji,J., Dagda, R.K., Jiang, J.F., Tyurina, Y.Y., Kapralov, A.A., Tyurin, V.A., Yanamala, N., Shrivastava, I.H., Mohammadyani, D., Qiang Wang, K.Z., Zhu, J., Klein-Seetharaman, J., Balasubramanian, K., Amoscato, A.A., Borisenko, G., Huang, Z., Gusdon, A.M., Cheikhi, A., Baty, C. Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells. Nature Cell Biology. 2013; 15(10): 1197-205.
Raghavan, V., Rbaibi, Y., Baty, C.J., Weisz, O.A. Rab11a-positive compartments in proximal tubule cells sort fluid-phase and membrane cargo. Cell Physiology. 2014; 306(5): C441-9.
Saurabh, S., Beck, L.E., Maji, S., Baty, C.J., Wang, Y., Yan, Q, Watkins, S.C, Bruchez, M.P. Multiplexed modular genetic targeting of quantum dots. ACS nano. 2014; 8(11): 11138-46.
Sponsored Research/Activities
Title: Endocytic Pathway Dysfunction in Dent Disease
Role: Co-Investigator
Funding Agency: National Institute of Diabetes, Digestive, & Kidney Disease
Grant Number: R01 DK125049
Start Year: 2020
End Year: 2025
Title: Proximal Tubule Endocytosis in Normal and Nephrotic Kidneys
Role: Co-Investigator
Funding Agency: National Institute of Diabetes, Digestive, & Kidney Disease
Grant Number: R01 DK118726
Start Year: 2019
End Year: 2023
Title: Interventions to Reduce Hypercoagulability in Old SIV-Infected NHPs
Role: Co-Investigator
Funding Agency: National Heart, Lung, & Blood Institute
Grant Number: R01 HL123096
Start Year: 2015
End Year: 2020