Department of Medicine
Faculty Profiles by Division

Department of Medicine

Faculty Profiles

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photo Charles Horn, PhD


Professor of Medicine

Member, Biobehavioral Oncology Program, UPMC Hillman Cancer Center

Graduate training faculty, Center for Neuroscience, University of Pittsburgh

Member, Pittsburgh Center for Pain Research


Phone: 412-623-1417

Office: UPMC Hillman Cancer Center - Research Pavilion, 1.19d
5117 Centre Avenue
Pittsburgh, PA 15213
Phone: 412-623-1417
Fax: 412-623-1119
Administrative Assistant:
Dianna Fennel
Address: 5117 Centre Avenue
Pittsburgh, PA 15213
Phone: 412-623-1114
Fax: 412-623-1415
Education and Training
Ph.D., Behavioral Neuroscience, Kansas State University, 1996
M.S., Behavioral Neuroscience, Kansas State University, 1993
B.S., Psychology, Missouri State University, 1991
Postdoctoral fellowship, Columbia University, Center for Neurobiology and Behavior, New York City, 2000
Research Interest
Dr. Horn's primary research is the neurobiology of vagus nerve signaling. This research uses neuromodulation devices to control nerve-organ communication for the treatment of cancer, inflammation, gastrointestinal motility, and side effects of cancer therapies.
For my complete bibliography, Click Here.
Selected Publications:
Lothet EH, Shaw KM, Lu H, Zhuo J, Wang YT, Gu S, Stolz DB, Jansen ED, Horn CC, Chiel HJ, Jenkins MW. Selective inhibition of small-diameter axons using infrared light. Scientific Reports. 2017; 7: 3275.
Gupta RG, Schafer C, Ramaroson Y, Sciullo MG, Horn CC. Role of the abdominal vagus and hindbrain in inhalational anesthesia-induced vomiting. Autonomic Neuroscience. 2017; 202: 114-121.
Rosenberg DM, Horn CC. Neurophysiological analytics for all! Free open-source software tools for documenting, analyzing, visualizing, and sharing using electronic notebooks. Journal of Neurophysiology. 2016.
Horn CC, Zirpel L, Sciullo MG, Rosenberg DM. Impact of electrical stimulation of the stomach on gastric distension-induced emesis in the musk shrew. Neurogastroenterology and Motility. 2016.
Donovan HS, Hagan TL, Campbell GB, Boisen MM, Rosenblum LM, Edwards RP, Bovbjerg DH, Horn CC. Nausea as a sentinel symptom for cytotoxic chemotherapy effects on the gut-brain axis among women receiving treatment for recurrent ovarian cancer: an exploratory analysis. Support Care Cancer. 2016; 24(6): 2635-42.
Horn CC, Yates BJ. Biology and control of nausea and vomiting 2015: Perspectives and overview of the conference. Autonomic Neuroscience. 2016; 202: 3-4.
Notable Achievements
Member, Pittsburgh Center for Pain Research, 2010 - Present
Member, American Physiological Society, 2007 - Present
Member, Society for Neuroscience, 1992 - Present
Cyclic Vomiting Syndrome Association, USA/Canada, Medical Advisory Board Primary Core Member, 2014-Present
Chair, NIH SPARC Cross-Team Communication Committee, 2017-Present
Co-Chair, NIH Stimulating Peripheral Activity to Relieve Conditions (SPARC) program steering committee (NIH Common Fund), 2015-2017