Department of Medicine
Faculty Profiles by Division

Department of Medicine

Faculty Profiles

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photo Jane W. Marsh, PhD

Infectious Diseases

Email: jwmarsh@pitt.edu

Phone: 412-648-3102

Contact
Office: Scaife Hall, Suite 865
3550 Terrace Street
Pittsburgh, PA 15261
 
Phone: 412-648-3102
Fax: 412-648-8455
E-mail: jwmarsh@pitt.edu
Education and Training
Education
PhD, Dartmouth College, 1998
BA, University of Vermont, 1982
Research Interest
Dr. Marsh is the Director of the Microbial Genomics Epidemiology Laboratory (MiGEL) and works closely with MiGEL Principal Investigator, Dr. Lee H. Harrison to investigate genomic epidemiology of hospital acquired infections. Current research is focused on integration of whole genome sequences of important multi-drug resistant bacteria from hospitalized patients with the electronic health record to enhance detection of hospital-associated transmission. MiGEL works closely with Infection Prevention to investigate genetic relationships of patient bacterial isolates suspected of being hospital acquired. Timely reporting of results enables rapid implementation of appropriate interventions to prevent further transmission and outbreaks. Other research interests include investigation of the human gut microbiome for prediction and transmission of infectious diseases as well as global genomic epidemiology and population structure of Neisseria meningitidis.
Publications
For my complete bibliography, Click Here.
Selected Publications:
Marsh, JW, Mustapha MM, Griffith MP, Evans DR, Ezeonwuka C, Pasculle AW, Shutt KA, Sundermann A, Ayres AM, Shields RK, Babiker A, Cooper VS, Van Tyne D, Harrison LH. Evolution of Outbreak-Causing Carbapenem-Resistant Klebsiella pneumoniae ST258 at a Tertiary Care Hospital over Eight Years. mBio. 2019; 10(5): 314813386.
Sunderman AJ, Babiker A, Marsh JW, Shutt KA, Mustapha MM, Pasculle AW, Ezeonwuka, C, Saul MI, Pacey MP, Van Tyne D, Ayres AM, Cooper VS, Snyder GM, Harrison LH. Outbreak of Vancomycin-resistant Enterococcus faecium in Interventional Radiology: Detection Through Whole Genome Sequencing-Based Surveillance. Clinical Infectious Diseases. 2019; 31312842.
Babiker A, Mustapha MM, Pacey MP, Shutt KA, Ezeonwuka CD, Ohm SL, Cooper VS, Marsh JW, Doi Y, Harrison LH. The use of Online Tools for Antimicrobial Resistance Prediction by Whole Genome Sequencing in MRSA and VRE. Journal of Global Antimicrobial Resistance. 2019; 19: 136-143.
Sundermann A, Miller JK, Marsh JW, Saul MI, Shutt KA, Pacey MP, Mustapha MM, Ayres A, Pasculle AW, Chen J, Dubrawski AW, Harrison LH. Automated Data Mining of the Electronic Health Record for Investigation of Healthcare-Associated Outbreaks. Infection Control & Hospital Epidemiology. 2019; 40(3): 314-319.
Miller JK, Chen J, Sunderman A, Marsh JW, Saul MI, Shutt KA, Pacey M, Mustapha MM, Harrison LH, Dubrawski A. Statistical outbreak detection by joining medical records and pathogen similarity. Journal of Biomedical Informatics. 2011; 91:103126: 30771483.
Marsh, JW, Pacey MP, Ezeonwuka C, Ohm SL, Snyder D, Cooper VS, Harrison LH, Doi Y, Mustapha MM. Clostridioides difficile: a potential source of NpmA in the clinical environment. Journal of Antimicrobial Chemotherapy. 2019; 74(2): 521-523.
Marsh JW, Galdys AL, Delgado E, Pasculle AW, Pacey MP, Ayres AM, Metzger A, Harrison LH, Muto CA. Bronchoscope-associated clusters of multidrug-resistant Pseudomonas aeruginosa and carbapenem-resistant Klebsiella pneumoniae. Infection Control & Hospital Epidemiology. 2019; 40(1): 40-46.
Sponsored Research/Activities
Title: Enhanced Detection System for Healthcare-Associated Transmission of Infection
Role: Co-Investigator
Funding Agency: National Institute of Allergy & Infectious Diseases
Grant Number: R01 AI127472
Start Year: 2016
End Year: 2021
Title: Genomic Epidemiology for Hospital Outbreak Detection
Role: Co-Investigator
Funding Agency: National Institute of Allergy & Infectious Diseases
Grant Number: R21 AI109459
Start Year: 2014
End Year: 2016