Department of Medicine
Faculty Profiles by Division

Department of Medicine

Faculty Profiles

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photo Nicolas Montalbetti, PhD


Instructor of Medicine


Phone: 412-648-9277

Phone: 412-648-9277
Administrative Assistant:
Maria Delesio
Address: S974 - Scaife Hall
3550 Terrace St
Pittsburgh, PA 15261
Phone: 412-383-9753
Research Interest
Dr. Montalbetti is examining the role of the umbrella cell layer in health and disease states. The interior of the bladder is covered by the urothelium, a stratified epithelium. Umbrella cells, the outer most cell layer in the urothelium, form an impermeable barrier that prevents the diffusion of urine constituents into the bladder interstititum. The goals of this project are to understand how umbrella cells maintain an impermeable barrier as bladders fill and deflate, and to understand how changes in urothelial permeability lead to disease states.
Sponsored Research/Activities
Title: Mechanisms underlying bladder-mediated pain in a mouse model of urinary tract infection
Role: Principal Investigator
Funding Agency: Urology Care Foundation
Grant Number: RES
Start Year: 2020
End Year: 2022
Title: Psysiological Properties of Human Kidney Organoids
Role: Co-Investigator
Funding Agency: University of Southern California/ National Institute of Diabetes, Digestive, & Kidney Disease
Grant Number: U01 DK107350
Start Year: 2018
End Year: 2019