Department of Medicine
Faculty Profiles by Division

Department of Medicine

Faculty Profiles

[Return To Index page]
photo Minh-Hong Nguyen, MD

Infectious Diseases

Professor of Medicine

Director, Transplant Infectious Diseases

Director, Antimicrobial Management Program

Email: nguyenh@dom.pitt.edu

Phone: 412-647-0996

Contact
Office: University of Pittsburgh, ID Division
3550 Fifth Avenue, Suite S872 Scaife Hall
Pittsburgh, PA 15261
 
Phone: 412-647-0996
Fax: 412-648-8455
E-mail: nguyenh@dom.pitt.edu
Administrative Assistant:
Megan Moore
Email: MFM62@pitt.edu
Phone: 412-624-9583
Education and Training
Education
B.S. - Chemistry and Physics, Elizabeth College, Elizabethtown, PA, 1984
M.D., Temple University School of Medicine, 1988
Training
Residency - Internal Medicine, University of Pittsburgh, School of Medicine, 1991
Fellowship - Infectious Diseases, University of Pittsburgh Health Center, 1995
Research Interest
Dr. Nguyen's multiple research interests are medical mycology research, including projects on the mechanisms and clinical impact of antifungal drug resistance, and molecular pathogenesis of invasive Candida infections. Since 2016, she extended her interest in Zygomycetes genetics and epidemiology. In addition, her research focuses on XDR bacterial and antimicrobial stewardship research, including projects on evolution and tolerance/resistance and pathogenic mechanisms of carbapenem-resistant Enterobacteriaceae (CRE) and other Gram negative bacteria; the development of novel antibiotic treatment strategies based upon bacterial genetics and pharmacokinetic-pharmacodynamic (PK-PD) principles; the clinical and economic impact of XDR infections and antimicrobial stewardship interventions; and clinical trials of new antimicrobials and diagnostic tests. Dr. Nguyen's Transplant Infectious Diseases (TID) research includes projects on the role of the microbiome in infections and outcomes among transplant recipients, the impact of rectal CRE carriage on transplant patients' outcome, and clinical studies and trials on a wide range of opportunistic fungal, bacterial, and viral infections.
Publications
Selected Publications:
Cheng, S, Clancy, CJ, Xu, W, Schneider, F, Hao, B, Mitchell, AP, Nguyen, MH. Profiling of Candida albicans gene expression during intra-abdominal candidiasis identifies biologic processes involved in pathogenesis. Journal of Infectious Diseases. 2013; 208(9): 1529-37.
Cheng, S, Clancy, CJ, Hartman, DJ, Hao, B, Nguyen, MH. Candida glabrata intra-abdominal candidiasis is characterized by persistence within the peritoneal cavity and abscesses. Infection and Immunity. 2014; 82(7): 3015-22.
Vergidis, P, Clancy, CJ, Shields, RK, Park, SY, Wildfeuer, BN, Simmons, RL, Nguyen, MH. Intra-Abdominal Candidiasis: The Importance of Early Source Control and Antifungal Treatment. PLoS One. 2016; 11(4): e0153247.
Eschenauer, GA, Kwak, EJ, Humar, A, Potoski, BA, Clarke, LG, Shields, RK, Abdel-Massih, R, Silveira, FP, Vergidis, P, Clancy, CJ, Nguyen, MH. Targeted versus universal antifungal prophylaxis among liver transplant recipients. American Journal of Transplantation. 2015; 15(1): 180-9.
Haidar, G, Alkroud, A, Cheng, S, Churilla, TM, Churilla, BM, Shields, RK, Doi, Y, Clancy, CJ, Nguyen, MH. Association between presence of aminoglycoside modifying enzymes and in vitro activity of gentamicin, tobramycin, amikacin and plazomicin against KPC and ESBL-producing Enterobacter spp. Antimicrobial Agents and Chemotherapy. 2015; AAC.00869-16.
Sponsored Research/Activities
Title: Physician burden in managing Cytomegalovirus (CMV) infection in donor +/ recipient – kidney transplant patients
Role: Principal Investigator
Funding Agency: Merck
Start Year: 2020
End Year: 2022
Title: Aspergillosis complicating severe influenza
Role: Principal Investigator
Funding Agency: National Institute of Aging
Grant Number: R21 AI153575
Start Year: 2020
End Year: 2022
Title: BAL Specimens
Role: Principal Investigator
Funding Agency: Pattern Biosciences
Grant Number: RES
Start Year: 2020
End Year: 2022
Title: Physician burden in managing Cytomegalovirus (CMV) infection in donor +/ recipient – kidney transplant patients
Role: Principal Investigator
Funding Agency: Merck
Start Year: 2020
End Year: 2022
Title: A cost analysis and compare the health resource utilization (HCRU) of primary antifungal prophylaxis
Role: Principal Investigator
Funding Agency: Astellas Pharma US
Grant Number: RES HCRU ISA
Start Year: 2020
End Year: 2021
Title: Real-world experience of Imipenem-Relebactam for treating Pseudomonas aeruginosa infection in clinics
Role: Principal Investigator
Funding Agency: Merck
Grant Number: RES 58784
Start Year: 2020
End Year: 2021
Title: CLSI Broth microdilution study
Role: Principal Investigator
Funding Agency: Pulmocide, Ltd
Start Year: 2019
End Year: 2020
Title: In vitro activity of Ibrexafungerp
Role: Principal Investigator
Funding Agency: Scynexis, Inc.
Start Year: 2019
End Year: 2020
Title: Chromosomal and Plasmid Contributions to Colistin Resistance and Virulence in KPC-Producing Klebsiella Pneumoniae
Role: Principal Investigator
Funding Agency: National Institute of Allergy & Infectious Diseases
Grant Number: R21 AI128338
Start Year: 2016
End Year: 2018
Title: Evaluation of In Vitro Activity of Fosfomycin Alone or in Combination with Newly Introduced ß-Lactam Agents Against Carbapenem-Resistant Pseudomonas Aeruginosa and Enterobacteriaceae Clinical Isolates
Role: Principal Investigator
Funding Agency: Zavante Therapeutics, Inc.
Grant Number: RES
Start Year: 2016
End Year: 2017
Title: Candida Albicans Gene Expression During Intra-abdominal Infections
Role: Principal Investigator
Funding Agency: National Institute of Allergy & Infectious Diseases
Grant Number: R21 AI107290
Start Year: 2014
End Year: 2017
Title: T2MR Study in SICU Patients at High Risk for Intra-abdominal Candidiasis
Role: Co-Investigator
Funding Agency: Centre Hospitalier Universitaire Vaudois
Start Year: 2018
End Year: 2019
Title: Epidemiology of CRE and MRSA Transmission: Patient and Organism Factors
Role: Co-Investigator
Funding Agency: University of Maryland
Grant Number: R01 AI121146
Start Year: 2018
End Year: 2019
Title: Imaging and PK-PD of Micafungin at Site of Candida Glabrata Infection In Vivo
Role: Co-Investigator
Funding Agency: National Institute of Allergy & Infectious Diseases
Grant Number: R21 AI121555
Start Year: 2015
End Year: 2017