Department of Medicine
Faculty Profiles by Division

Division of Geriatric Medicine

Faculty Profiles

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photo Subashan Perera, PhD

Geriatrics

Professor of Medicine and Biostatistics

Core Co-Leader & Senior Statistician, Data Management and Analysis Core of the Pittsburgh Claude D. Pepper Older Americans Independence Center

Email: ksp9@pitt.edu

Phone: 412-692-2365

Contact
Office: 3471 Fifth Avenue
Kaufmann Medical Building, Suite 500
Pittsburgh, PA 15213
 
Phone: 412-692-2365
Fax: 412-692-2370
E-mail: ksp9@pitt.edu
Administrative Assistant:
Beth Thomas
Address: 3471 Fifth Ave, Suite 500
Kaufmann Medical Bldg
Pittsburgh, PA 15213
Email: eat8@pitt.edu
Phone: 412-864-2507
Fax: 412-692-2370
Education and Training
Education
BS, Computer Science, University of Wisconsin-Eau Claire, 1992
MS, Mathematics, Kansas State University, 1994
MS, Statistics, Kansas State University, 1996
PhD, Statistics, Kansas State University, 2000
Research Interest
Dr. Perera is a biostatistician with interests in aging, clinical trials, time series analysis, item response theory, and classification and regression trees. His work has involved estimating criteria for clinically meaningful change in physical performance measures of the elderly, examining their association with future outcomes using large data sets, and using item response theory to analyze rating scales used in elderly populations. Dr. Perera co-leads the Data Management, Analysis and Informatics Core of our Pepper Center, in addition to serving as lead statistician in multiple funded NIH, AHRQ and VA grants within and outside of the Division.
Publications
For my complete bibliography, Click Here.
Selected Publications:
Perera S, Nadkarni NK, Wert D, VanSwearingen J, Brach JS. Intraclass correlation coefficients for cluster randomized trials in community-dwelling older adults. Journal of Aging and Health. 2020; 32: 252-258.
Perera S, VanSwearingen J, Shuman V, Brach JS. Assessing gait efficacy in older adults: an analysis using item response theory. Gait & Posture. 2020; 77(3): 118-124.
Perera S, Nace DA, Resnick NM, Greenspan SL. The nursing home physical performance test: a secondary data analysis of women in long-term care using item response theory. The Gerontologist. 2018; 58: e197-e204.
Perera S, Patel KV, Rosano C, Chandler JM, Newman A, Cauley J, Guralnik J, Ferrucci L, Studenski S. Gait Speed Predicts Incident Disability: A Pooled Analysis. Journal of Gerontology-Series A: Biological Sciences & Medical Sciences. 2016; 71: 63-71.
Studenski S, Perera S, Patel K. Gait Speed and Survival in Older Adults. Journal of the American Medical Association. 2011; 305: 50-58.
Perera S, Studenski SA, Newman AB, Simonsick EM, Harris T, Schwartz A, Visser M. Are Estimates of Meaningful Decline in Mobility Performance Consistent among Clinically Important Subgroups?. Journal of Gerontology: Medical Sciences. 2014; 69A: 1260-1268.
Perera S. Normal theory and bootstrap confidence interval estimation for assessing diagnostic performance gain when combining two diagnostic tests. Communications in Statistics-Series B: Simulation and Computation. 2008; 37: 2076-2088.
Perera S. Maximum quasi-likelihood estimation for the NEAR(2) model. Journal of Time Series Analysis. 2004; 25: 723-732.
Perera S. Approximate Bayes estimation of parameters of the NEAR(2) model. Far East Journal of Theoretical Statistics. 2004; 14: 203-213.
Perera S. Maximum quasilikelihood estimation for a simplified NEAR(1) model. Statistics & Probability Letters. 2002; 58: 147-155.
Sponsored Research/Activities
Title: Investigation of brain mechanisms involved in Urgency Urinary Incontinence
Role: Co-Investigator
Funding Agency: National Institute of Aging
Grant Number: R01 AG06425
Start Year: 2019
End Year: 2024
Title: The Effect of Reducing Sedentary Behavior on Sleep and Cardiovascular Health
Role: Co-Investigator
Funding Agency: National Heart, Lung, & Blood Institute
Grant Number: R01 HL147610
Start Year: 2019
End Year: 2023
Title: Nitrite Therapy to Improve Mitochondrial Energetics and Physical Activity in Older Adults
Role: Co-Investigator
Funding Agency: National Institute of Aging
Grant Number: R01 AG058883
Start Year: 2019
End Year: 2022
Title: MyHealthAge: Immune Fingerprinting Signatures in Predicting Successful Aging
Role: Co-Investigator
Funding Agency: Aging Institute of UPMC
Start Year: 2019
End Year: 2020
Title: Modified Application of Cardiac Rehabilitation for Older Adults (MACRO)
Role: Co-Investigator
Funding Agency: National Institute of Aging
Grant Number: R01 AG060499
Start Year: 2018
End Year: 2023
Title: Restoring Central Motor Control to Improve Community Mobility of Older Adults
Role: Co-Investigator
Funding Agency: National Institute of Aging
Grant Number: R01 AG057671
Start Year: 2018
End Year: 2022
Title: Midcareer Investigator Award in Translational Patient-Oriented Research in Aging
Role: Co-Investigator
Funding Agency: National Institute of Aging
Grant Number: K24 AG057728
Start Year: 2017
End Year: 2022
Title: Sustaining Skeletal Health in Frail Elderly
Role: Co-Investigator
Funding Agency: National Institute of Aging
Grant Number: R01 AG052123
Start Year: 2016
End Year: 2021
Title: Autoimmunity and Emphysema and Risk of Osteoporosis in Smokers
Role: Co-Investigator
Funding Agency: National Heart, Lung, & Blood Institute
Grant Number: R01 HL128289
Start Year: 2016
End Year: 2021
Title: Task Specific Timing and Coordination Exercises to Improve Mobility in Older Adults
Role: Co-Investigator
Funding Agency: National Institute of Aging
Grant Number: R01 AG045252
Start Year: 2015
End Year: 2020
Title: Understanding Patient-Specific Deficits Causing Step Asymmetry Post-Stroke: A Step Towards Personalizing Gait Rehabilitation
Role: Co-Investigator
Funding Agency: American Heart Association-Great Rivers
Start Year: 2015
End Year: 2018
Title: Biomarkers Predictive of Lung Function in Decline in Physiologically Normal Smokers
Role: Co-Investigator
Funding Agency: National Heart, Lung, & Blood Institute
Grant Number: R21 HL129917
Start Year: 2015
End Year: 2017
Title: The Role of Teriparatide for Healing of Atypical Femoral Shaft Fractures
Role: Co-Investigator
Funding Agency: Eli Lilly Company
Start Year: 2012
End Year: 2017
Title: Innovative Approach to Geriatric Osteoporosis
Role: Biostatistician
Funding Agency: National Institute of Aging
Grant Number: R01 AG066825
Start Year: 2020
End Year: 2025
Title: Enhancing Recovery of SCI-Induced Bladder Dysfunction Using Small Molecules
Role: Biostatistician
Funding Agency: Department of Defense
Grant Number: RES
Start Year: 2018
End Year: 2021
Title: Patient-Centered versus Imaging-Directed Care for Older Veterans with Chronic LBP
Role: Biostatistician
Funding Agency: US Department of Veterans Affairs
Grant Number: RES
Start Year: 2018
End Year: 2019
Title: Effect of Reducing Sedentary Behavior on Blood Pressure
Role: Biostatistician
Funding Agency: National Heart, Lung, & Blood Institute
Grant Number: R01 HL134809
Start Year: 2017
End Year: 2022
Title: Instrumental Screening for Dysphagia by Combining High-Resolution Cervical Auscultation with Advanced Data Analysis Tools to Identify Silent Dysphagia and Silent Aspiration
Role: Biostatistician
Funding Agency: National Institute of Child Health & Human Development
Grant Number: R01 HD092239
Start Year: 2017
End Year: 2021
Title: Further Enhancing Treatment of Urgency Incontinence
Role: Biostatistician
Funding Agency: National Institute of Aging
Grant Number: R56 AG059427
Start Year: 2017
End Year: 2018
Title: A New Genus of Ubiquitin-Based Anti-Inflammatories for COPD
Role: Biostatistician
Funding Agency: National Heart, Lung, & Blood Institute
Grant Number: UH2 HL123520
Start Year: 2016
End Year: 2019
Title: Patient-Centered versus Imaging Directed Care of Older Veterans with Chronic LBP
Role: Biostatistician
Funding Agency: Veterans Affairs Pittsburgh Healthcare System
Grant Number: IPA
Start Year: 2016
End Year: 2018
Title: Nitrite Benefits to Mediate Fatigability in Older HFpEF Patients
Role: Biostatistician
Funding Agency: National Institute of Aging
Grant Number: R56 AG051637
Start Year: 2016
End Year: 2017
Title: Maintenance of Skeletal Integrity in Frail Elders - Phase 2
Role: Biostatistician
Funding Agency: National Institute of Aging
Grant Number: R01 AG050302
Start Year: 2015
End Year: 2020
Title: The Aging Brain and the Cognition - Mobility Interface in Clinically Normal Older Adults
Role: Biostatistician
Funding Agency: National Institute of Aging
Grant Number: K23 AG049945
Start Year: 2015
End Year: 2020
Title: Improving Outcomes of UTI in LTC Facilities: The IOU Study
Role: Biostatistician
Funding Agency: Agency for Healthcare Research and Quality
Grant Number: R18 HS023779
Start Year: 2015
End Year: 2018
Title: IPA - Perera
Role: Biostatistician
Funding Agency: Veterans Affairs Pittsburgh Healthcare System
Grant Number: IPA
Start Year: 2015
End Year: 2017
Title: A New Genus of Ubiquitin-Based Anti-Inflammatories for COPD
Role: Biostatistician
Funding Agency: National Heart, Lung, & Blood Institute
Grant Number: UH3 HL123520
Start Year: 2014
End Year: 2019
Title: Mechanisms/Treatments of Lower Urinary Tract Dysfunction After Spinal Cord Injury - Core B
Role: Biostatistician
Funding Agency: National Institute of Diabetes, Digestive, & Kidney Disease
Grant Number: P01 DK093424
Start Year: 2013
End Year: 2018
Title: Mechanisms/Treatments of Lower Urinary Tract Dysfunction After Spinal Cord Injury
Role: Biostatistician
Funding Agency: National Institute of Diabetes, Digestive, & Kidney Disease
Grant Number: P01 DK093424
Start Year: 2013
End Year: 2018
Title: PITTSBURGH OLDER AMERICANS INDEPENDENCE CENTER
Role: Co-Leader
Funding Agency: National Institute of Aging
Grant Number: P30 AG024827
Start Year: 2020
End Year: 2025
Title: PDE5 Inhibition of Afferents and Interstitial Cells in Overactive Mouse Bladders
Role: Collaborator
Funding Agency: National Institute of Health
Grant Number: R01 DK098361
Start Year: 2020
End Year: 2025
Title: Pittsburgh Older Americans Independence Center DMAC
Role: Core Leader
Funding Agency: National Institute of Aging
Grant Number: P30 AG024827
Start Year: 2015
End Year: 2020
Title: Cell Autonomous and Non-Autonomous Mechanisms of Aging - Core A
Role: Core Leader
Funding Agency: Scripps Research Institute/National Institute of Aging
Grant Number: P01 AG043376
Start Year: 2013
End Year: 2018
Title: Impact of Behavioral Treatment of Insomnia on Nighttime Urine Production
Role: Statistician
Funding Agency: National Institute of Aging
Grant Number: R21 AG060292
Start Year: 2018
End Year: 2020
Notable Achievements
Fellow, Gerontological Society of America, 2018
Highly Cited Researcher Recognition, Thomson Reuters (www.highlycited.com), 2014
Honorable Mention, Clinical Medicine Research Award, Gerontological Society of America, 2005
Outstanding Senior Award, University of Wisconsin-Eau Claire, 1992
Leonard and Dorellen Haas Scholarship, University of Wisconsin-Eau Claire, 1990