Department of Medicine
Faculty Profiles by Division

Division of Gastroenterology, Hepatology and Nutrition

Faculty Profiles

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photo Juliane I. Beier, PhD



Phone: 412-648-4186

Office: Thomas E. Starzl Biomedical Science Tower
200 Lothrop Street, West 1146
Pittsburgh, 15213
Phone: 412-648-4186
Education and Training
B.S., Heinrich-Heine University, Duesseldorf, Germany, 1999
M.S., Heinrich-Heine University, Duesseldorf, Germany, 2001
Ph.D., Heinrich-Heine University, Duesseldorf, Germany, 2005
Postdoctoral Fellow, University of Louisville, Louisville, KY, 2005
Research Interest
Our research focus is on environmental vinyl chloride exposure in the context of existing underlying liver disease. Clearly high occupational exposure to vinyl chloride is directly hepatotoxic; what is less well clear is the impact of lower environmental exposure on exacerbating existing liver disease. Given the fact that a significant portion of the population has risk factors for liver disease (most commonly, obesity), and that 30% of the US population has elevated indices of liver damage, any potential impact of low environmental exposure could be dramatic. Our findings indicate that indeed vinyl chloride will exacerbate liver damage caused by another factor. This work shifts the paradigm of current risk assessment for not only this compound, but any other environmental agent that may potentially damage the liver.
For my complete bibliography, Click Here.
Selected Publications:
Lang, A.L., Chen, L., Poff, G.D., Ding, W.X., Barnett, R.A., Arteel, G.E., Beier, J.I. Vinyl chloride dysregulates metabolic homeostasis and enhances diet-induced liver injury in mice. Hepatology Communications. 2018; 2: 270-284.
Lang, A.L., Beier, J.I. Interaction of volatile organic compounds and underlying liver disease: a new paradigm for risk. Biological Chemistry. 2018; in press.
Sponsored Research/Activities
Title: Vinyl chloride-induced changes to the epitranscriptome: interaction with diet
Role: Principal Investigator
Funding Agency: National Institute of Environmental Health Sciences
Grant Number: R21 ES031531
Start Year: 2020
End Year: 2022
Notable Achievements
Member, Gesellschaft für Biochemie und Molekularbiologie, Germany (GBM), 2003-2010
Member, American Association for the Study of Liver Diseases (AASLD), 2007-present
Member, International Society for Hepatic Sinusoidal Research (ISHSR), 2010-present
Member, Society of Toxicology (SOT), 2013-present
Appointed Member, American Association for the Study of Liver Diseases (AASLD) Education Committee, 2013-2015
Abstract Review Board, member, American Association for the Study of Liver Diseases (AASLD), 2015-present
Abstract Review Board, member, Digestive Disease Week (DDW), 2015-present
Ad Hoc Reviewer, Scientific Review Panel, 2016/10 ZRG1 DKUS-C (82) A, for PA-13-313: Academic Research Enhancement Award (AREA), 2016
Ad Hoc Reviewer, Scientific Review Panel, 2017/10 ZRG1 DKUS-H (54) R, for PAR-16-064: Small Grants for New Investigators to Promote Diversity in Health-Related Research (R21), 2017
Ad Hoc Reviewer, AJP: GI; Annals of Hepatology; ABB; Hepatology; JPET; Journal of Hepatology; TAAP; ToxSci, 2008-present