Department of Medicine
Faculty Profiles by Division

Division of Gastroenterology, Hepatology and Nutrition

Faculty Profiles

[Return To Index page]
photo Michael S Gold, PhD


Professor, Department of Neurobiology


Phone: 412-383-5367

Office: University of Pittsburgh Department of Neurobiology
3500 Terrace Street Rm E1440 BST
Pittsburgh, PA 15213
Phone: 412-383-5367
Fax: 412-383-8663
Education and Training
BA, University of California at Berkley, Berkley, CA, 1987
PhD, University of California at Los Angeles, L.A, CA, 1994
Post-doc, University of California at San Francisco, SF, CA, 1995
Post-doc, University of California at Los Angeles, LA, CA, 1997
Research Interest
Dr. Gold is a Professor of Anesthesiology whose research is focused around the clinical features of a number of pain syndromes. These observations include the following: 1) many pain syndromes are unique to a particular part of the body such as the head in migraine, the temporomandibular joint in temporomandibular disorder (TMD), or the colon in inflammatory bowel disease (IBD); 2) many pain syndromes such as migraine, TMD, and IBD occur with a greater prevalence, severity, and/or duration in women than in men; 3) many pain syndromes are associated with changes in the excitability of primary afferent neurons; 4) there are time dependent changes in the mechanisms underlying pain syndromes; and 5) different types of injuries (i.e., inflammation or nerve injury) are differentially sensitive to therapeutic interventions. These observations led to specific hypotheses that are tested in ongoing studies in the Gold laboratory. These include 1) characterizing the mechanisms underlying inflammation-induced changes in the evoked Ca2+ transients in sensory neurons, 2) characterizing the mechanisms underlying the inflammatory mediator-induced sensitization of dural afferents, 3) characterizing the influence of estrogen on the excitability of spinal and trigeminal ganglion neurons, 4) characterizing the mechanisms underlying the link between stress and migraine, 5) characterizing the role of changes in inhibitory receptors, in particular GABA, in injury-induced increases in sensitivity, and 6) identification of ways to maximize the therapeutic utility of local anesthetics. The ultimate goal of these studies is to identify novel targets for the development of therapeutic interventions for the treatment of pain.
For my complete bibliography, Click Here.
Notable Achievements
President, US Association for the Study of Pain, 2020
Visiting Professor, Nihon University, 2018
Chair, Scientific Program Committee, International Association for the Study Pain, 2018
Cahir, Scientific Program Committee, American Pain Society, 2017
American Pain Society’s Fredrick Kerr Basic Science Research Award, 2016
Chair, NIH Study Section NST-2, 2016
Regular Member NIH Study Section NST-2, 2014
Executive Committee, North American Pain School, 2014
Member of the Foundation for Anesthesia Education and Research (FAER) Academy of Research Mentors in Anesthesiology, 2012
American Pain Society's John C. Liebeskind Early Career Achievement Award, 2001