Department of Medicine
Faculty Profiles by Division

Division of Gastroenterology, Hepatology and Nutrition

Faculty Profiles

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photo Georgios I. Papachristou, MD, PhD


Phone: 412-647-8132

Office: Div. of Gastroenterolgy, Hepatology, & Nutrition
UPMC Presbyterian Hospital M2, C Wing
Pittsburgh, PA 15213
Phone: 412-647-8132
Fax: 412-647-1880
Administrative Assistant:
Terri Wetmore
Address: Division of Gastroenterology, Hepatology & Nutrition-200 Lothrop St
UPMC Presbyterian Hospital M2, C Wing.
Pittsburgh, PA 15213
Phone: 412-647-8132
Fax: 412-647-1880
Education and Training
MD, University of Patras Medical School, Patras, Greece, 1996
PhD, University of Patras Medical Schoo, Patrax, Greece, 2007
Certificate in Clinical Research, University of Pittsburgh Medical School, Pittsburgh, PA, 2005
Internal Medicine, Albany Medical College, Albany, NY, 2002
Gastroenterology, University of Pittsburgh Medical School, Pittsburgh, PA, 2005
Advanced Endoscopy, Mayo Clinic, Rochester, MN, 2006
Research Interest
Dr. Papachristou’s research interests center on acute pancreatitis. Dr. Papachristou leads a number of institutional studies and multi-center collaborations. He is the principal investigator in the Post-Acute Pancreatitis Pancreatic Exocrine Insufficiency (PAPPEI) trial, a prospective, multicenter study, which evaluates the incidence of exocrine pancreatic insufficiency and long-term quality of life in subjects after an attack of acute pancreatitis. Dr. Papachristou is also the site principal investigator for a multicenter randomized trial entitled Stent versus Indomethacin (SVI), which compares different preventive treatments for post-ERCP acute pancreatitis. He also leads APPRENTICE (Acute Pancreatitis Patient Registry To Examine Novel Therapies In Clinical Experiences), an international consortium for acute pancreatitis care involving 22 centers throughout the world. Additionally, Dr. Papachristou directs a translational research laboratory focusing on the genetic basis, immunology, and inflammatory responses in acute pancreatitis. His current research funding is from the National Institute of Health, industry, and private donors. Dr. Papachristou has authored over 100 peer reviewed articles and book chapters.
Clinical Interest
Georgios Papachristou, MD PhD is an Associate Professor of Medicine at the University of Pittsburgh School of Medicine. He is an advanced endoscopist who specializes in pancreaticobiliary diseases and practices state–of–the–art ERCP and endoscopic ultrasound (EUS). Board–certified in Gastroenterology, Dr. Papachristou received his medical degree from the University of Patras School of Medicine in Greece graduating first in his class (summa cum lade). He completed training in Gastroenterology at the University of Pittsburgh and advanced endoscopy at the Mayo Clinic in Rochester, MN.
Educational Interest
Dr. Papachristou is a Fellow of the American Society for Gastrointestinal Endoscopy (FASGE) and American Gastroenterological Association (AGAF). He is an active member and serves in scientific committees in all major GI professional organizations.
For my complete bibliography, Click Here.
Selected Publications:
Mounzer R, Langmead C, Wu BU, Evans A, Slivka A, Whitcomb DC, Yadav D, Banks P, Papachristou GI. “Comparison of Existing Clinical Scoring Systems to Predict Persistent Organ Failure in Patients with Acute Pancreatitis". Gastroenterology. 2012; 142(7): 1476-82.
Yadav D, O'Connell M, Papachristou GI. “Natural History Following the First Attack of Acute Pancreatitis”. American Journal of Gastroenterology. 2012; 107(7): 1096-103.
Wu BU, Bakker OJ, Papachristou GI, et al. “Blood urea nitrogen in the early assessment of acute pancreatitis: an international validation study”. Archives of Internal Medicine. 2011; 171(7): 669-76.
Gardner TB, Coelho-Prabhu N, Gordon SR, Gelrud A, Maple JT, Papachristou GI, et al. “Direct endoscopic necrosectomy for the treatment of walled-off pancreatic necrosis: results from a multicenter U.S. series”. Gastrointestinal Endoscopy. 2011; 73(4): 718-26.
Papachristou GI, Abu-Elmagd KM, Bond G, et al. “Pancreaticobiliary complications after composite visceral transplantation: incidence, risk, and management strategies”. Gastrointestinal Endoscopy. 2011; 73(6): 1165-73.
Stevens T, Lopez R, Adler DG, Al-Haddad MA, Conway J, Dewitt JM, Forsmark CE, Papachristou GI, et al. “Multicenter comparison of the interobserver agreement of standard EUS scoring and Rosemont classification scoring for diagnosis of chronic pancreatitis”. Gastrointestinal Endoscopy. 2010; 71(3): 519-26.
Papachristou GI, Muddana V, Yadav D, et al. “Comparison of BISAP, Ranson's, APACHE-II, and CTSI Scores in Predicting Organ Failure, Complications, and Mortality in Acute Pancreatitis”. Americal Journal of Gastroenterology. 2010; 105(2): 435-41.
Gleeson FC, Clain JE, Papachristou GI, et al. “Prospective assessment of EUS criteria for lymphadenopathy associated with rectal cancer”. Gastrointestinal Endoscopy. 2009; 69(4): 896-903.
Muddana V, Whitcomb DC, Khalid A, Slivka A, Papachristou GI. “Elevated serum creatinine as a marker of pancreatic necrosis in acute pancreatitis”. American Journal of Gastroenterology. 2009; 104(1): 164-70.
Sponsored Research/Activities
Title: Assessment of Gastrointestinal Symptoms and Weight Loss After Acute Pancreatitis
Role: Principal Investigator
Funding Agency: Abbvie. Inc.
Grant Number: RES
Start Year: 2018
End Year: 2019
Title: Incidence of Exocine Pancreatic Insufficiency, Nutritional Deficiencies, and Impaired Quality of Life Following an Attack of Acute Pancreatitis
Role: Principal Investigator
Funding Agency: Abbvie. Inc.
Grant Number: RES
Start Year: 2017
End Year: 2020
Title: VA IPA - Stello
Role: Principal Investigator
Funding Agency: Veterans Affairs Pittsburgh Healthcare System
Grant Number: IPA
Start Year: 2012
End Year: 2016
Title: Results of Ercp in Sphincter of Oddi Dysfunction (RESPOND)
Role: Co-Principal Investigator
Funding Agency: Medical University of South Carolina
Grant Number: R01 DK115495
Start Year: 2017
End Year: 2022
Title: Mechanism of Systemic Inflammation-Associated Endothelial and Epithelial Cell Dysfunction Following Acute Pancreatitis, Trauma and Burns
Role: Co-Investigator
Funding Agency: Department of Defense
Grant Number: RES W81XWH-17-1-0502
Start Year: 2017
End Year: 2020
Title: Stent vs. Indomethacin
Role: Co-Investigator
Funding Agency: Medical University of South Carolina/National Institute of Diabetes, Digestive, & Kidney Disease
Grant Number: U01 DK104833
Start Year: 2015
End Year: 2020
Title: A Randomized Controlled Pilot Trial of Indomethacin in Acute Pancreatitis
Role: Co-Investigator
Funding Agency: American College of Gastroenterology
Start Year: 2013
End Year: 2016
Notable Achievements
Fellow American Society of Gastrointestinal Endoscopy (FASGE), 2012
American Gastroenterology Association Fellow (AGAF), 2014
Chairman, American College of Gastroenterology Abstract Review Committee, Pancreaticobiliary Section, 2013
Region Councilor, Pennsylvania Society of Gastroenterology (PSG), 2015
Treasurer, Collaborative Alliance for Pancreas Education & Research (CAPER), 2016