Department of Medicine
Faculty Profiles by Division

Division of Gastroenterology, Hepatology and Nutrition

Faculty Profiles

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photo Jami L. Saloman, PhD

Gastroenterology

Assistant Professor of Medicine

Assistant Professor of Neurobiology, Secondary Appointment

Executive Committee, Pittsburgh Center for Pain Research

Email: jls354@pitt.edu

Phone: 412-383-5120

Contact
Office: 200 Lothrop St. BSTWR E1457
Mail: , Mezz, UPMC Presbyterian
Pittsburgh, PA 15213
 
Phone: 412-383-5120
Fax: 412-648-4055
E-mail: jls354@pitt.edu
Education and Training
Education
B.A., Boston University, 2006
PhD, University of Maryland, Baltimore, 2013
Training
Post-Doc, University of Pittsburgh, 2017
Research Interest
The Saloman Lab uses both in vitro and in vivo animal models as well as clinical samples to conduct anatomical, behavioral, optogenetic, chemogenetic, Ca2+ Imaging, and cell/molecular studies to investigate the role of the nervous system in regulating homeostasis as well as pathological conditions, including pancreatitis pain and tumorigenesis. Currently, we are investigating several signaling mechanisms that contribute chronic pancreatitis pain. We are also focused on the role of peripheral nerves and neuro-immune interactions that regulate tumorigenesis and cancer pain.
Publications
For my complete bibliography, Click Here.
Selected Publications:
Saloman JL, Cohen JA, Kaplan DH. Intimate Neuro-immune Interactions: Breaking Barriers Between Systems to Make Meangingful Progress. Curr Opin Neurobiol. 2019; 62: 60-67.
Saloman JL, Albers KM, Li D, Hartman DJ, Crawford HC, Muha EA, Rhim AD, Davis BM. Ablation of Sensory Neurons in a Genetic Model of Pancreatic Ductal Adenocarcinoma Slows Initiation and Progression of cancer. Proc Natl Acad Sci USA. 2016; 113(11): 3078-83.
Saloman JL, Scheff NN, Snyder LM, Ross SE, Davis BM, Gold MS. Gi-DREADD Expression in Peripheral Nerves Produces Ligand-Dependent Analgesia, as well as Ligand-Independent Functional Changes in Sensory Neurons. J Neurosci. 2016; 36(42): 10769-81.
Saloman JL, Singhi AD, Hartman DJ, Normolle DP, Albers KM, Davis BM. Systemic Depletion of Nerve Growth Factor Inhibits Disease Progression in a Genetically Engineered Model of Pancreatic Ductal Adenocarcinoma. Pancreas. 2018; 47(7): 856-63.
Sponsored Research/Activities
Title: Mechanism-based Approach to Pain in Chronic Pancreatitis (MAP-CP)
Role: Principal Investigator
Funding Agency: National Institute of Diabetes, Digestive, & Kidney Disease
Grant Number: R21 DK122293453
Start Year: 2020
End Year: 2022
Title: Neuropathic vs. inflammatory pain in chronic pancreatitis: can unique biomarkers be identified to guide mechanistic approaches to pain treatment?
Role: Principal Investigator
Funding Agency: National Institute of Diabetes, Digestive, & Kidney Disease
Grant Number: K01 DK120737
Start Year: 2019
End Year: 2024
Title: Chemical Pancreatectomy for Chronic Pancreatitis and Pancreatic Cancer
Role: Co-Investigator
Funding Agency: National Institute of Diabetes, Digestive, & Kidney Disease
Grant Number: R01 DK120698
Start Year: 2019
End Year: 2023
Notable Achievements
Member, Biobehavioral Oncology Program, Hillman Cancer Center, 2019-present
Member, Pittsburgh Center for Pain Research, 2017-present
Member, International Association for the Study of Pain, 2009-present
Member, American Pancreas Association, 2018-present
Member, American Gastroenterological Association, 2020-present
Member, US Association for the Study of Pain, 2020-present
Member, Society for Neuroscience, 2007-present