Department of Medicine
Faculty Profiles by Division

Division of Hematology/Oncology

Faculty Profiles
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photo Wentao Gao, MD, PhD

Hematology/Oncology

Research Assistant Professor of Medicine

Email: gaow2@upmc.edu

Phone: 412-908-9771
Contact
Office: UPMC Hillman Cancer Center
5150 Centre Avenue, Lab 1.3
Pittsburgh, PA 15232
 
Phone: 412-908-9771
Fax: 412-623-7704
E-mail: gaow2@upmc.edu
Education and Training
Education
MD, Norman Bethune University of Medical Sciences, 1990
Master of Oral & Maxillofacial Pathology, Norman Bethune University of Medical Sciences, 1993
PhD of Oral & Maxillofacial Pathology, Norman Bethune University of Medical Sciences, 1998
Training
Visting Scholar, University of Hong Kong Institute of Molecular Biology, 1996
posdoctoral, University of Pittsburgh, 2000
Research Interest
Molecular cell biology, Autophagy signaling pathway and application, cell death signaling pathways including apoptosis, pyroptosis and necroptosis and their applications, infectious disease vaccine development, cancer biology and immunotherapy.
Publications
For my complete bibliography, Click Here.
Selected Publications:
Li J, Chen Z,, Stang MT, Gao W. Transiently expressed ATG16L1 inhibits autophagosome biogenesis and aberrantly targets RAB11-positive recycling endosomes. Autophagy. 2017; Feb;13(2): 345-358.
Chen X, Khambu B, Zhang H,, Gao W, Li M, Chen X, Yoshimori T, Yin XM. Autophagy induced by calcium phosphate precipitates targets damaged endosomes. Journal of Biological Chemistry. 2014; Apr 18;289(16): 11162-74.
Wang W,, Chen Z, Billiar TR, Stang MT, Gao W. The Carboxyl-Terminal Amino Acids Render Pro-Human LC3B Migration Similar to Lipidated LC3B in SDS-PAGE. Public Library of Science PLoS One. 2013; Sep 10; 8(9): e74222.
Gao W, Chen Z,, Wang W, Stang MT. E1-like activating enzyme Atg7 is preferentially sequestered into p62 aggregates via its interaction with LC3-I. Public Library of Science PLoS One. 2013; Sep 10; 8(9): e74222.
Sun Q, Gao W, Loughran P, Shapiro R, Fan J, Billiar TR, Scott MJ. Caspase 1 activation is protective against hepatocyte cell death by up-regulating beclin 1 protein and mitochondrial autophagy in the setting of redox stress. Journal of Biological Chemistry. 2013; May 31; 288(22): 15947-58.
Chen X, Min Li,, Chen DH, Gao W,, Guan JL, Komatsu M,, Yin XM. Autophagy induced by calcium phosphate precipitates involves endoplasmic reticulum membranes in autophagosome biogenesis. Public Library of Science PLoS ONE. 2012; 7(12): e52347.
Gao W, Kang JH, Liao Y, Ding WX, Gambotto A, Watkins SC, Liu YJ, Stolz DB, Yin XM. Biochemical isolation and characterization of the tubulovesicular LC3-positive autophagosomal compartment. Journal of Biological Chemistry. 2010; 285(2): 1371.
Steitz J,, Wagner RA, Bristol T, Gao W, Donis RO, Gambotto A. Assessment of route of administration and dose escalation for an adenovirus-based influenza A virus (H5N1) vaccine in chickens. Clinical and Vaccine Immunology. 2010; 17(9): 1467-72.
Ding WX,, Li M, Chen X, Ni HM,, Lin CW, Gao W, Lu B,, Stolz DB, Clemens DL, Yin XM. Autophagy reduces acute ethanol-induced hepatotoxicity and steatosis in mice. Gastroenterology. 2010; 139(5): 1740-52.
Ni HM, Baty CJ, Li N, Ding WX,, Gao W,, Li M, Chen X,, Ma J,, Michalopoulos GK, Yin XM. Bid agonist regulates murine hepatocyte proliferation by controlling endoplasmic reticulum calcium homeostasis. Hepatology. 2010; 52(1): 338-48.
Notable Achievements
Highest Honor MD graduate, 1990
Highest Honor PhD graduate, 1998
Ivy Wu Scholarship, 1996
Pitt Innovator Award, 2006
Membership of the American Association of Immunologists, 2004-
Membership of American Society of Gene Therapy, 2001-

Division Websites

Cardiology

Endocrinology and Metabolism

Gastroenterology, Hepatology and Nutrition

General Internal Medicine

Geriatric Medicine
Hematology/Oncology

Infectious Diseases

Pulmonary, Allergy and Critical Care Medicine

Renal-Electrolyte

Rheumatology and Clinical Immunology

Contact

Department of Medicine
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3550 Terrace Street
Pittsburgh, PA 15261
Email:  chairoff@pitt.edu
Phone:  412-648-9636
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