Department of Medicine
Faculty Profiles by Division

Division of Hematology/Oncology

Faculty Profiles

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photo Amma Twumwa Owusu-Ansah, MD

Assistant Professor of Medicine

Clinical Director, Center for Translational and International Hematology


Phone: 412-624-7821

Office: Biomedical Science Tower
1252 E BST
Pittsburgh, PA
Phone: 412-624-7821
Education and Training
MB. CHB, University of Ghana Medical School, 1997
Pediatric Internship and Residency, John H Stroger Hospital of Cook County, Chicago IL, 2004
Pediatric Hematology/Oncology, Case Western Reserve University Rainbow Babies & Children's Hospital, Cleveland OH, 2012
Research Interest
Dr. Owusu-Ansah's primary research interest is in translating novel or repurposed therapeutics into clinical settings to prevent or halt the progression of complications of sickle cell disease. Her other interests are in global health and implementation research, specifically identifying strategies to improve access to state-of-the-art medical care for individuals with benign hematologic disorders in different demographic regions of the world. Up to 50% of her research effort is spent in Ghana, West Africa.
She is the Principal Investigator of an Investigator-initiated Phase Ib trial of NVX-508 in adults with sickle cell disease being conducted at the Noguchi Memorial Institute for Medical Research, University of Ghana in Accra, Ghana ( Identifier NCT03013426)
Clinical Interest
Dr. Owusa-Ansah is a pediatric hematologist and oncologist who serves as a teaching and attending physician on the Inpatient and Consult hematology service, Children's Hospital of Pittsburgh of UPMC, 7 weeks year and is Co-Director of the sickle cell team.
Educational Interest
Her passion is to make the study and practice of benign hematology interesting, straightforward and relevant to medical students, residents and fellows through interactive lectures, problem solving and teaching rounds on the inpatient service.
For my complete bibliography, Click Here.
Selected Publications:
Tsaras G, Owusu-Ansah A, Boateng FO, Amoateng-Adjepong Y. Complications associated with sickle cell trait: a brief narrative review. American Journal of Medicine. 2009; 122(6): 507-12.
Owusu-Ansah A, Choi SH, Petrosiute A, Letterio JJ, Huang AY. Triterpenoid inducers of Nrf2 signaling as potential therapeutic agents in sickle cell disease: a review. Frontier Medicine. 2014; 9(1): 46-56.
Owusu-Ansah A, Ihunnah CA, Walker AL, Ofori-Acquah SF. Inflammatory targets of therapy in sickle cell disease. Translational Research. 2015; 167(1): 281-97.
Ghosh S, Ihunnah CA, Hansen JM, Archer DR, Owusu-Ansah AT, Ofori-Acquah SF. Nonhematopoietic Nrf2 dominantly impedes adult progression of sickle cell anemia in mice. Journal of Clinical Investigation Insight. 2016; 1(4): e81090.
Anie, K.A., Paintsil, V., Owusu-Dabo, E., Ansong, D., Osei-Akoto, A., Ohene-Frempong, K., Amissah, K.A., Addofoh, N., Ackah, E.B., Owusu-Ansah, A.T., Ofori-Acquah, S.F. Organ Damage in sickle cell disease study (ORDISS: protocol for a longitudinal cohort study based in Ghana. British Medical Journal Open. 2017; :7(8).
Benneh-Akwasi Kuma, A., Owusu-Ansah, A.T., Ampomah, M.A., Sey, F., Olayemi, E., Nouraie, M., Ofori-Acquah, S.F. Prevalence of relative systemic hypertension in adults with sickle cell disease in Ghana. PLoS One. 2018; :13(1).
Kwarteng-Siaw, M., Paintsil, V., Korankye Toboh, C., Owusu-Ansah, A., Green, N. Assessment of Transition Readiness in Adolescents with Sickle Cell Disease and their Caretakers. a single institution experience. International Journal of Hematology Research. 2017; :3(1): 171-179.
Sponsored Research/Activities
Title: Hemostasis and Vascular Biology Research Institute - Ofori-Acquah
Role: Co-Investigator
Funding Agency: Hemophilia Center of Western PA
Start Year: 2013
End Year: 2018
Notable Achievements
Member, American Society of Hematology, 2011-present
Member, American Society of Pediatric Hematology and Oncology, 2011-present
Global Sickle Cell Disease Network, 2010-present