Department of Medicine
Faculty Profiles by Division

Division of Hematology/Oncology

Faculty Profiles

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photo Dan Paul Zandberg, MD


Associate Professor of Medicine

Director, Head and Neck and Thyroid Cancer Disease Sections

Medical Oncology Co-Leader of the UPMC Hillman Head and Neck Cancer Program


Phone: 412-648-6589

Office: 5150 Centre Avenue
Pittsburgh, PA 15232
Phone: 412-648-6589
Fax: 412-648-6579
Administrative Assistant:
Alice Petrovich
Address: 5150 Centre Avenue, 5th floor
Pittsburgh, PA 15232
Phone: 412-648-6589
Fax: 412-648-6579
Education and Training
BA, University of Delaware, Newark, DE, 2001
MD, Jefferson Medical College, Philadelphia, PA, 2005
Residency, George Washington University Medical Center, Washington DC, 2008
Fellowship, University of Maryland Hematology/Oncology, 2012
Research Interest
Dr. Zandberg is a translational and clinical researcher. His primary interest is the development of novel immunotherapy trials to improve outcomes in recurrent/metastatic squamous cell carcinoma of the head and neck.
Clinical Interest
Dr. Zandberg's clinical interests include head and neck and thyroid cancers as well as cutaneous squamous cell carcinoma of the head and neck
Selected Publications:
Zandberg, DP, Strome SE. The role of the PD-L1:PD-1 pathway in squamous cell carcinoma of the head and neck. Oral Oncology. 2014; 50(7): 627-32.
Zandberg, DP, Bhargava, R, Badin, S, Cullen, KJ. The role of human papillomavirus in nongenital cancers. CA Cancer J Clin. 2013 Jan;63(1):57-81. CA: A Cancer Journal for Clinicians. 2013; 63(1): 57-81.
Zandberg, DP, Liu, S, Goloubeva, O, Schumaker LM, Cullen KJ. Emergence of HPV16 positive oropharyngeal cancer in black patients over time: University of Maryland 1992-2007. Cancer Prevention Research. 2015; 8(1): 12-9.
Zandberg DP, Rollins S, Goloubeva O, Morales RE, Tan M, Taylor R, Wolf JS, Schumaker LM, Cullen KJ, Zimrin A, Ord R, Lubek JE, Suntharalingam M, Papadimitriou JC, Mann D, Strome SE, Edelman MJ. A phase I dose escalation trial of MAGE-A3- and HPV16-specific peptide immunomodulatory vaccines in patients with recurrent/metastatic (RM) squamous cell carcinoma of the head and neck (SCCHN). Cancer Immunology Immunotherapy. 2015; 64(3): 367-79.
Liu SZ, Zandberg DP, Schumaker LM, Papadimitriou JC, Cullen KJ. Correlation of p16 expression and HPV type with survival in oropharyngeal squamous cell cancer. Oral Oncology. 2015; 51(9): 862-9.
Zandberg DP, Liu S, Goloubeva O, Ord R, Strome SE, Suntharalingam M, Taylor R, Morales RE, Wolf JS, Zimrin A, Lubek JE, Schumaker LM, Cullen KJ. Oropharyngeal cancer (OPC) drives racial outcome disparities in squamous cell carcinoma of the head and neck (HNSCC): Ten-year experience at the university of maryland greenebaum cancer center (UMGCC). Head & Neck. 2016; 38(4): 564-72.
Pai, SI, Zandberg, DP, Strome, SE. The role of antagonists of the PD-1:PD-L1/PD-L2 axis in head and neck cancer treatment. Oral Oncology. 2016; 61: 152-8.
Varki V, Ioffe OB, Bentzen SM, Heath J, Cellini A, Feliciano J, Zandberg DP. PD-L1, B7-H3, and PD-1 expression in immunocompetent versus immunosuppressed patients with cutaneous squamous-cell carcinoma. Cancer Immunology Immunotherapy. 2018; 67(5): 805-814.
Notable Achievements
NCI Calabresi Scholar Award, 2012
Alliance Scholar Award, 2018
NCI Cancer Clinical Investigator Team Leadership Award (CCITLA), 2019
Leo H. Criep, MD Excellence in Patient Care Award, 2019-2020
Castle Connolly Regional Top Doctor 2020, 2020
Castle Connolly Regional Top Doctor 2021, 2021