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My research focuses on functional genomics and systems biology studies of common chronic illnesses, affecting brain, neurobehavior, and metabolism, diseases caused by stress or infections with viral pathogens (SIV/HIV). Many of chronic diseases manifest in chronic inflammation and impaired aging. I am using a combination of genomic, transcriptomic, and epigenetic approaches to unravel mechanisms of such aging- and inflammation-related phenotypes and identify targets for therapy. I am also interested in natural protective mechanisms that natural hosts have developed during a long-term coevolution with the pathogens.
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