Department of Medicine
Faculty Profiles by Division

Division of Infectious Diseases

Faculty Profiles

[Return To Index page]
photo Daria Van Tyne, PhD

Email: VANTYNE@pitt.edu

Phone: 412-648-4210

Contact
Office: S853 Scaife Hall
3550 Terrace Street
Pittsburgh, PA 15261
 
Phone: 412-648-4210
Fax: 412-648-8521
E-mail: VANTYNE@pitt.edu
Administrative Assistant:
Tanya Gonzales
Address: 869 Scaife Hall
3550 Terrace Street
Pittsburgh, PA 15261
Email: tal67@pitt.edu
Phone: 412-648-8510
Fax: 412-648-8521
Administrative Assistant:
Gabriella Merritt
Address: 817 Scaife Hall
3550 Terrace Street
Pittsburgh, PA 15261
Email: gmm76@pitt.edu
Phone: 412-383-9062
Fax: 412-648-8521
Education and Training
Education
BA, Vassar College, 2006
PhD, Harvard University, 2013
Training
Postdoctoral Fellow, Harvard Medical School/Massachusetts Eye and Ear Infirmary, 2018
Research Interest
The Van Tyne Lab studies how bacteria evolve to become superbugs, using comparative genomics and functional analysis. Our research falls into two main areas. First, we work to understand how bacteria evolve during human infection to resist antibiotics and host immune defenses. We sequence bacterial strains from human infections and use functional genomics to identify and characterize novel resistance mechanisms. These include the ability of bacteria to resist the host immune system, or to persist in the face of antibiotic pressure. Second, we help develop new approaches to treat resistant bacterial infections more effectively. We help characterize new types of antibiotics, and establish how novel compounds kill bacteria. We are also exploring how bacteriophages could be developed into next-generation antibacterials.