Department of Medicine
Faculty Profiles by Division

Division of Pulmonary, Allergy and Critical Care Medicine

Faculty Profiles

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photo Bryan J. McVerry, MD

Pulmonary, Allergy and Critical Care Medicine

Associate Professor of Medicine

Associate Professor of Environmental and Occupational Health

Associate Professor of Clinical and Translational Science

Email: mcverrybj@upmc.edu

Phone: 412-648-3098

Contact
Office: UPMC Montefiore Hospital, NW628
3459 Fifth Avenue
Pittsburgh, PA 15213
 
Phone: 412-648-3098
Fax: 412-383-7113
E-mail: mcverrybj@upmc.edu
Administrative Assistant:
Brittany Manning
Email: manningb2@upmc.edu
Phone: 412-648-3098
Fax: 412-383-7113
Education and Training
Education
BS, Lehigh University, 1992
MD, Georgetown University, 1997
Training
Residency, Internal Medicine, University of Chicago Hospital, 2000
Post-Doctoral Research Fellowship, Emergency Medicine, University of Chicago, Pritzker School of Medicine, 2001
Post-Doctoral Clinical and Research Fellowship, Pulmonary and Critical Care, Johns Hopkins University School of Medicine, 2005
Research Interest
Dr. McVerry’s research interest is focused on translational investigation of the biological mechanisms underlying the development and consequences of sepsis and acute lung injury. His research efforts are designed to span the continuum from the bench to the bedside. Currently interests include: 1) contributions of the host microbiome to the evolution of and outcomes following critical illness, 2) mechanisms of glucose homeostasis and regulation of host response to nutritional support in critical illness, 3) biological phenotypes of critical illness and the impact on treatment decisions and outcomes, 4) mechanisms underlying the development of cognitive impairment in critically ill patients, and 5) development of novel therapeutic strategies for prevention and treatment of acute respiratory failure in the context of pneumonia and/or sepsis.
Clinical Interest
Dr. McVerry’s clinical interest and expertise focuses on the care of critically ill patients in the medical ICU, specifically those with acute lung injury and ARDS. He has additional interest in early implementation of physical rehabilitation in critically ill patients, in minimizing sedation to facilitate physical rehabilitation in mechanically ventilated patients, in endocrine dysregulation in critical illness, and in quality improvement in the Medical ICU.
Educational Interest
Dr. McVerry's educational interest focuses on the development of academic physicians as clinicians, educators, and scientists.
Publications
For my complete bibliography, Click Here.
Selected Publications:
Kitsios GD, Yang L, Manatakis DV, Nouraie SM, Evankovich J, Bain W, Dunlap DD, Shah F, Barbash IJ, Rapport SF, Zhang Y, DeSensi RS, Weathington NM, Chen BB, Ray P, Mallampalli RK, Benos P, Lee JS, Morris A, McVerry BJ. ARDS subphenotypes beyond ARDS: prognostic enrichment in mechanically-ventilated patients with or at risk for ARDS. Crit Care Med. 2019; In Press.
National Heart, Lung, and Blood Institute PETAL Clinical Trials Network. Early Neuromuscular Blockade in the Acute Respiratory Distress Syndrome. N Engl J Med. 2019; 380(21): 1997-2008.
Shah FA, Kitsios GD, Zhang Y, Morris A, Yende S, Huang D, O'Donnell CP, McVerry BJ. Rationale for and Design of the Study of Early Enteral Dextrose in Sepsis: A Pilot Randomized Controlled Trial. JPEN. 2019; doi: 10.1002/jpen.1608: [Epubaheadofprint].
Matthay MA, Calfee CS, Zhuo H, Thompson BT, Wilson JG, Levitt JE, Rogers AJ, Gotts JE, Wiener-Kronish JP, Bajwa EK, Donahoe MP, McVerry BJ. Allogeneic Mesenchymal Stromal Cells for Treatment of Moderate to Severe ARDS (START): A Randomized Phase 2a Safety Trial. Lancet Respiratory Medicine. 2019; Feb; 7(2): 154-162.
Kitsios GD, Fitch A, Manatakis DV, Rapport SF, Li K, Qin S, Huwe J, Zhang Y, Doi Y, Methé B, Benos P, Morris A, McVerry BJ. Respiratory microbiome profiling as a diagnostic tool for bacterial pneumonia in mechanically ventilated patients. Front Microbiol. 2018; 9:1413: doi:10.3389/fmicb.2018.01413.
Shah FA, Singamsetty S, Guo L, Chuan BW, McDonald S, Cooper BA, O'Donnell BJ, Stefanovski D, Wice B, Zhang Y, O'Donnell CP, McVerry BJ. Stimulation of the Endogenous Incretin Glucose-Dependent Insulinotropic Peptide by Enteral Dextrose Improves Glucose Homeostasis and Inflammation in Murine Endotoxemia. Transl Res. 2018; Mar;193:1-12: doi:10.1016/j.trsl.2017.11.001.
Sponsored Research/Activities
Title: Epigenetic Changes and Delirium After Intensive Care Unit Admission
Role: Co-Investigator
Funding Agency: National Institute of Aging
Grant Number: R21
Start Year: 2019
End Year: 2021
Title: Combination of Extracorporeal Life Support and Mesenchymal Stem Cell Therapy for Treatment of ARDS in Combat Casualties and Evacuation of Service Members with ARDS
Role: Co-Investigator
Funding Agency: Army
Start Year: 2015
End Year: 2017
Title: Cardiolipin as a Novel Mediator of Acute Lung Injury - Core C
Role: Co-Investigator
Funding Agency: National Heart, Lung, & Blood Institute
Grant Number: P01 HL114453
Start Year: 2014
End Year: 2018
Title: Antidote for Inhaled CO Poisoning Based on Mutationally Engineered Neuroglobin
Role: Co-Investigator
Funding Agency: National Heart, Lung, & Blood Institute
Grant Number: R01 HL125886
Start Year: 2014
End Year: 2018
Title: Mechanisms of Lung Homeostatis by F box Proteins
Role: Co-Investigator
Funding Agency: National Heart, Lung, & Blood Institute
Grant Number: R01 HL097376
Start Year: 2014
End Year: 2018
Title: RV/PA Recoupling by Bone Marrow Derived Mesenchymal Stem Cells
Role: Co-Investigator
Funding Agency: National Heart, Lung, & Blood Institute
Grant Number: R01 HL114795
Start Year: 2012
End Year: 2017
Title: Core B-Immunosuppression in acute lung injury
Role: Core Leader
Funding Agency: Ohio State University/ National Heart, Lung, & Blood Institute
Grant Number: P01 HL114453
Start Year: 2019
End Year: 2024
Notable Achievements
Alpha Omega Alpha, Georgetown University School Medicine, 1996
Resuscitation Science Research Fellowship, Univ of Chicago Dept of Medicine, 2000-2001
Individual Ruth L. Kirschstein National Research Service Award (F32), 2004-2005
Ironman Triathalon Finisher, 2004 & 2008
NIH Mentored Clinical Scientist Research Career Development Award (K08), 2007-2012
Conferral of Tenure, 2017