Department of Medicine
Faculty Profiles by Division

Division of Renal-Electrolyte

Faculty Profiles
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photo Mohammad Al-bataineh, DVM, MS, PhD

Renal-Electrolyte

Assistant Professor of Medicine

Email: mma57@pitt.edu

Phone: 412-624-2619
Contact
Office: 3550 Terrace Street
931 Scaife Hall
Pittsburgh, PA 15261
 
Phone: 412-624-2619
Fax:
E-mail: mma57@pitt.edu
Education and Training
Education
Doctor of Veterinary Medicine, Jordan University of Science and Technology, 2000
M.S., Physiology & Pharmacology, Jordan University of Science and Technology, 2002
Ph.D., Clinical Pharmacology, Kansas State University, 2010
Post-doctoral Associate, University of Pittsburgh, 2012
Post-doctoral Scholar, University of Pittsburgh, 2016
Research Interest
Dr. Al-bataineh is a DVM-PhD scientist, who studies epithelial transport physiology and kidney pathophysiology. His research studies the mechanism of metabolic regulation of cellular, organ and body homeostasis through cell surface expression of epithelial membrane transporters. Presently, Dr. Al-bataineh is interested in understanding the acute and chronic effects of the cell surface sensor Mucin 1 (MUC1) during metabolic stress conditions, such as ischemia-reperfusion injury (IRI) and acid-base disorders. In his training and research projects, Dr. Al-bataineh has employed both animal and cell culture model systems and developed expertise in renal physiology, and kidney histology, microscopy, and pathophysiology. He has spearheaded several significant research projects resulting in publications in high-impact journals such as Nature Chemical Biology, Journal of Proteome Research, and American Journal of Physiology. Dr. Al-bataineh has been PI on two NIH grants (NRSA, and K01), and one pharmaceutical fellowship award (SANOFI). He has received several awards from national societies, including the Epithelial Transport Group of the American Physiological Society (APS), and the Steve Hebert Award Session of the Experimental Biology (EB). Beyond his research success, Dr. Al-bataineh has been fortunate to obtain a wide-range of teaching experiences. He has had the opportunity to teach a variety of courses (with Labs) including Human Physiology, Animal Physiology, and Pharmacology. Moreover, he has supervised many students and provides them with an appropriate feedback after evaluating their progress. Dr. Al-bataineh also serves as a reviewer in different Journals.
Publications
For my complete bibliography, Click Here.
Selected Publications:
Al-Bataineh MM, Sutton TA, Hughey RP. Novel roles for mucin 1 in the kidney. Current Opinion in Nephrology and Hypertension. 2017; 26(5): SEP 2017: 384–391.
Al-Bataineh, MM, Kinlough, CL, Poland, PA, Pastor-Soler, NM, Sutton, TA, Mang, HE, Bastacky, SI, Gendler, SJ, Madsen, CS, Singh, S, Monga, SP, Hughey, RP. Muc1 enhances the beta-catenin protective pathway during ischemia-reperfusion injury. American journal of physiology. Renal physiology. 2016.
Al-Bataineh MM, Li H, Ohmi K, Gong F, Marciszyn AL, Naveed S, Zhu X, Neumann D, Wu Q, Cheng L, Fenton RA, Pastor-Soler NM, Hallows KR. Activation of the metabolic sensor AMP-activated protein kinase inhibits aquaporin-2 function in kidney principal cells. American journal of physiology. Renal physiology. 2016; Nov 1; 311(5): F890–F900.
Al-Bataineh, MM, Gong, F, Marciszyn, A, Myerburg, MM, Pastor-Soler, NM. Regulation of Proximal Tubule Vacuolar H+-ATPase by PKA and AMP-Activated Protein Kinase. American journal of physiology. Renal physiology. 2014; 306(9): F981-995.
Al-Bataineh, MM, Alzamora, R, Ohmi, K, Ho, PY, Marciszyn, A, Gong, F, Li, H, Hallows, KR, Pastor-Soler, NM. Aurora Kinase A Activates the Vacuolar H+-ATPase (V-ATPase) in Kidney Carcinoma Cells. American journal of physiology. Renal physiology. 2016.
Roy, A & Al-bataineh, MM, Pastor-Soler, NM. Collecting Duct Intercalated Cell Function and Regulation. Clinical journal of the American Society of Nephrology. 2015; 10(2): 305-324.
Gidon, A, Al-Bataineh, MM, Jean-Alphonse, FG, Stevenson, HP, Watanabe, T, Louet, C, Khatri, A, Calero, G, Pastor-Sole, NM, Gardella, TJ, Vilardaga, JP. Endosomal G protein-coupled receptor signaling turned off by negative feedback actions of PKA and v-ATPase. Nature chemical biology. 2014; 10(9): 707-709.
Alzamora, R, Al-Bataineh, MM, Liu, W, Gong, F, Li, H, Thali, RF, Joho-Auchli, Y, Brunisholz, RA, Satlin, LM, Neumann, D, Hallows, KR, Pastor-Soler, NM. AMP-activated protein kinase regulates the vacuolar H+-ATPase via direct phosphorylation of the A subunit (ATP6V1A) in the kidney. American journal of physiology. Renal physiology. 2013; 305(7): F943-956.
Pastor-Soler, NM, Sutton, TA, Mang, HE, Kinlough, CL, Gendler, SJ, Madsen, CS, Bastacky, SI, Ho, J, Al-Bataineh, MM, Hallows, KR, Singh, S, Monga, SP, Al-BKobayashi, H, Haase, VH, Hughey, RP. Muc1 is Protective in a Mouse Model of Kidney Ischemia-Reperfusion Injury. American journal of physiology. Renal physiology. 2015; 308(12): F1452-1462.
Rondanino, C, Poland, PA, Kinlough, CL, Li, H, Rbaibi, Y, Myerburg, MM, Al-bataineh, MM, Kashlan, OB, Pastor-Soler, NM, Hallows, KR, Weisz, OA, Apodaca, G, Hughey, RP. Galectin-7 modulates the length of the primary cilia and wound repair in polarized kidney epithelial cells. American journal of physiology. Renal physiology. 2011; 301(3): F622-633.
Sponsored Research/Activities
Title: Role of Muc1 in the B-Catenin Response to Acute Kidney Injury
Role: Principal Investigator
Funding Agency: National Institute of Diabetes, Digestive, & Kidney Disease
Grant Number: K01 DK109038
Start Year: 2016
End Year: 2021

Division Websites

Cardiology

Endocrinology and Metabolism

Gastroenterology, Hepatology and Nutrition

General Internal Medicine

Geriatric Medicine
Hematology/Oncology

Infectious Diseases

Pulmonary, Allergy and Critical Care Medicine

Renal-Electrolyte

Rheumatology and Clinical Immunology

Contact

Department of Medicine
1218 Scaife Hall
3550 Terrace Street
Pittsburgh, PA 15261
Email:  chairoff@pitt.edu
Phone:  412-648-9636
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